6-Fluoro-DMT

6-Fluoro-DMT

Clinical data
ATC code	none
Identifiers
IUPAC name 2-(6-fluoro-1H-indol-3-yl)-N,N-dimethyl-ethanamine
CAS Number	1511-31-5 Y
ChemSpider	26286731 Y
Chemical and physical data
Formula	C12H15FN2
Molar mass	206.264 g·mol−1
3D model (JSmol)	Interactive image
SMILES CN(CCC1=CNC2=C1C=CC(F)=C2)C
InChI InChI=1S/C12H15FN2/c1-15(2)6-5-9-8-14-12-7-10(13)3-4-11(9)12/h3-4,7-8,14H,5-6H2,1-2H3 Y Key:DZXZPVGWRZCXDH-UHFFFAOYSA-N Y
(verify)

6-Fluoro-N,N-dimethyltryptamine (6-Fluoro-DMT) is a synthetic drug of the tryptamine chemical class.

Pharmacology

Binding profile

6-Fluoro-DMT possess affinity for the 5-HT_1A (392.6 nM), 5-HT_1B (217.7 nM), 5-HT_1D (55.4 nM), 5-HT_1E (460.8 nM), 5-HT_2A (866 nM), 5-HT_2B (29.8 nM), 5-HT_2C (674.2 nM), 5-HT_5A (960.5 nM), 5-HT₆ (25.6 nM), 5-HT₇ (40.8 nM), D₁ (547.3 nM), D₂ (610.4 nM), D₃ (866.8 nM), D₄ (1,454 nM), D₅ (6,291 nM), α_1A-adrenergic (173.3 nM), α_2B-adrenergic (295.5 nM), α_2C-adrenergic (148.8 nM), H₁ (46.6 nM), H₂ (925.4 nM), I₁ (898.4 nM), ₁ (6,892 nM), and ₂ (7,128 nM) receptors, as well as the SERT (144.6 nM). It has low/negligible (> 10,000 nM) affinity for the 5-HT₃, α_1B-adrenergic, α_2A-adrenergic, β₁-adrenergic, β₂-adrenergic, H₃, H₄, and M₁-M₅ receptors, as well as the DAT and NET. It has not been screened at 5-HT_1F, 5-HT₄, α_1D-adrenergic, β₃-adrenergic, or VMAT₁/VMAT₂.

See also

• 5-Fluoro-DMT
• 5-Fluoro-αMT
• 5-Bromo-DMT
• 6-Fluoro-AMT
• 6-Fluoro-DET

External links

• 6-Fluoro-DET