BRL-54443

BRL-54443
Identifiers
	IUPAC name 3-(1-methylpiperidin-4-yl)-1H-indol-5-ol;
CAS Number	57477-39-1 ;
PubChem CID	2438;
IUPHAR/BPS	3927;
ChemSpider	2344 ;
UNII	Q2DH1CHI0Y;
CompTox Dashboard (EPA)	DTXSID40206089 ;
Chemical and physical data
Formula	C14H18N2O
Molar mass	230.311 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES Oc3ccc1c(c(c[nH]1)C2CCN(C)CC2)c3;
	InChI InChI=1S/C14H18N2O/c1-16-6-4-10(5-7-16)13-9-15-14-3-2-11(17)8-12(13)14/h2-3,8-10,15,17H,4-7H2,1H3 ; Key:WKNFADCGOAHBPG-UHFFFAOYSA-N ;
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BRL-54443 is a drug which acts as a selective agonist for the 5-HT_1E and 5-HT_1F serotonin receptor subtypes.^[1]^[2]

References

^ McKune CM, Watts SW (April 2001). "Characterization of the serotonin receptor mediating contraction in the mouse thoracic aorta and signal pathway coupling". The Journal of Pharmacology and Experimental Therapeutics. 297 (1): 88–95. PMID 11259531.
^ Janssen P, Tack J, Sifrim D, Meulemans AL, Lefebvre RA (May 2004). "Influence of 5-HT1 receptor agonists on feline stomach relaxation". European Journal of Pharmacology. 492 (2–3): 259–67. doi:10.1016/j.ejphar.2004.03.054. PMID 15178373.

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