Jump to content

N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline

From Wikipedia, the free encyclopedia
N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline[1]
Names
Preferred IUPAC name
Ethyl 2-ethoxyquinoline-1(2H)-carboxylate
Other names
Ethyl 1,2-dihydro-2-ethoxyquinoline-1-carboxylate
Identifiers
3D model (JSmol)
Abbreviations EEDQ
ECHA InfoCard 100.036.728 Edit this at Wikidata
UNII
  • CCOC1C=CC2=CC=CC=C2N1C(=O)OCC
Properties
C14H17NO3
Molar mass 247.29 g/mol
Melting point 62 to 67 °C (144 to 153 °F; 335 to 340 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
checkY verify (what is checkY☒N ?)

N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ) is an irreversible dopamine-receptor antagonist.[2]

EEDQ is also a highly specific reagent for carboxyl groups. It enables the coupling of acylamino acids with amino acid esters in high yield and without racemization.[3]

References

[edit]
  1. ^ 2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline at Sigma-Aldrich
  2. ^ Neuroscience Letters 1992, 137(2), p.265
  3. ^ https://www.bachem.com/


Stub icon

This article about a heterocyclic compound is a stub. You can help Wikipedia by expanding it.

Retrieved from "https://en.wikipedia.org/w/index.php?title=N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline&oldid=1147940122"