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Chemical compound
CAR-302,668
(1-methyl-3,6-dihydro-2H-pyridin-4-yl)methyl 2-hydroxy-3-methyl-2-phenylbutanoate
CAS Number PubChem CID ChemSpider Formula C 18 H 25 N O 3 Molar mass 303.402 g·mol−1 3D model (JSmol )
CC(C)C(C1=CC=CC=C1)(C(=O)OCC2=CCN(CC2)C)O
InChI=1S/C18H25NO3/c1-14(2)18(21,16-7-5-4-6-8-16)17(20)22-13-15-9-11-19(3)12-10-15/h4-9,14,21H,10-13H2,1-3H3
Key:VZCBERXKHILZBM-UHFFFAOYSA-N
CAR-302,668 (302668 , α-isopropylmandelic acid (1-methyl-1,2,3,6-tetrahydro-4-pyridyl)methyl ester ) is an anticholinergic deliriant drug,[ 1] invented under contract to Edgewood Arsenal in the 1960s. It is a reasonably potent incapacitating agent with an ED50 of 4μg/kg and a long duration of action of around 16-24 hours.[ 2]
^ US 4584378 , Treves GR, Baum BM, "Anticholinergic Compounds.", issued 22 April 1986, assigned to FMC Corp.
^ Ketchum JS (2006). Chemical Warfare Secrets Almost Forgotten. A Personal Story of Medical Testing of Army Volunteers with Incapacitating Chemical Agents During the Cold War . ChemBooks Inc. p. 320-326. ISBN 978-1-4243-0080-8 .
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