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Chemical compound
CAR-301,060
[(7R,8R)-7-methyl-1-azabicyclo[2.2.2]octan-8-yl]2-cyclopentyl-2-hydroxy-2-phenylacetate
PubChem CID ChemSpider CompTox Dashboard (EPA ) Formula C 21 H 29 N O 3 Molar mass 343.467 g·mol−1 3D model (JSmol )
C[C@@H]1[C@@H](C2CCN1CC2)OC(=O)C(C3CCCC3)(C4=CC=CC=C4)O
InChI=1S/C21H29NO3/c1-15-19(16-11-13-22(15)14-12-16)25-20(23)21(24,18-9-5-6-10-18)17-7-3-2-4-8-17/h2-4,7-8,15-16,18-19,24H,5-6,9-14H2,1H3/t15-,19+,21?/m1/s1
Key:ICYFZPARHUFDKQ-GAKLZJQJSA-N
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CAR-301,060 (also known as cis-2-Methyl-3-quinuclidinylphenylcyclopentylglycolate or just by its code number 301060 ) is a potent and long lasting anticholinergic deliriant drug, related to the chemical warfare agent 3-Quinuclidinyl benzilate (QNB). It was developed under contract to Edgewood Arsenal during the 1960s as part of the US military chemical weapons program , during research to improve upon the properties of earlier agents such as QNB.
CAR-301,060 was found to be slightly less potent than QNB, and with around the same duration of action, but with a very high central to peripheral effects ratio.[ 1] [ 2]
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