ZNF259

ZPR1
Identifiers
Aliases	ZPR1, ZNF259, ZPR1 zinc finger, GKAF
External IDs	OMIM: 603901; MGI: 1330262; HomoloGene: 2900; GeneCards: ZPR1; OMA:ZPR1 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	116,788,039 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	46,193,941 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; right testis; ; sperm; ; left testis; ; islet of Langerhans; ; sural nerve; ; Achilles tendon; ; body of pancreas; ; right lobe of liver; ; smooth muscle tissue;
	Top expressed in
	epiblast; ; tail of embryo; ; embryo; ; Rostral migratory stream; ; embryo; ; seminiferous tubule; ; genital tubercle; ; muscle of thigh; ; yolk sac; ; morula;
	More reference expression data
	n/a
Gene ontology
Molecular function	receptor tyrosine kinase binding; zinc ion binding; metal ion binding; protein binding; translation initiation factor binding;
Cellular component	cytoplasm; perikaryon; Cajal body; cell projection; growth cone; nucleoplasm; SMN complex; axon; soma; nucleolus; perinuclear region of cytoplasm; nucleus; gemini of coiled bodies;
Biological process	cell differentiation; axon development; pre-mRNA catabolic process; Cajal body organization; mRNA processing; apoptotic process involved in development; positive regulation of growth; inner cell mass cell proliferation; cellular response to epidermal growth factor stimulus; positive regulation of gene expression; regulation of myelination; positive regulation of transcription involved in G1/S transition of mitotic cell cycle; RNA splicing; spinal cord development; positive regulation of RNA splicing; positive regulation of protein import into nucleus; cell population proliferation; DNA endoreduplication; microtubule cytoskeleton organization; trophectodermal cell proliferation; signal transduction; negative regulation of motor neuron apoptotic process;
	Sources:Amigo / QuickGO
Orthologs
	8882
	22687
	ENSG00000109917
	ENSMUSG00000032078
	O75312
	Q62384
	NM_003904; NM_001317086
	NM_011752
	NP_001304015; NP_003895
	NP_035882
	Wikidata
View/Edit Human	View/Edit Mouse

Zinc finger protein ZPR1 is a protein that in humans is encoded by the ZNF259 gene.^[5]^[6]^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000109917 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000032078 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Galcheva-Gargova Z, Konstantinov KN, Wu IH, Klier FG, Barrett T, Davis RJ (June 1996). "Binding of zinc finger protein ZPR1 to the epidermal growth factor receptor". Science. 272 (5269): 1797–802. Bibcode:1996Sci...272.1797G. doi:10.1126/science.272.5269.1797. PMID 8650580. S2CID 6851783.
^ Galcheva-Gargova Z, Gangwani L, Konstantinov KN, Mikrut M, Theroux SJ, Enoch T, Davis RJ (October 1998). "The cytoplasmic zinc finger protein ZPR1 accumulates in the nucleolus of proliferating cells". Molecular Biology of the Cell. 9 (10): 2963–71. doi:10.1091/mbc.9.10.2963. PMC 25573. PMID 9763455.
^ "Entrez Gene: ZNF259 zinc finger protein 259".

External links

ZNF259+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article on a gene on human chromosome 11 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000109917 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000032078 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8650580-5] Galcheva-Gargova Z, Konstantinov KN, Wu IH, Klier FG, Barrett T, Davis RJ (June 1996). "Binding of zinc finger protein ZPR1 to the epidermal growth factor receptor". Science. 272 (5269): 1797–802. Bibcode:1996Sci...272.1797G. doi:10.1126/science.272.5269.1797. PMID 8650580. S2CID 6851783.

[pmid9763455-6] Galcheva-Gargova Z, Gangwani L, Konstantinov KN, Mikrut M, Theroux SJ, Enoch T, Davis RJ (October 1998). "The cytoplasmic zinc finger protein ZPR1 accumulates in the nucleolus of proliferating cells". Molecular Biology of the Cell. 9 (10): 2963–71. doi:10.1091/mbc.9.10.2963. PMC 25573. PMID 9763455.

[entrez-7] "Entrez Gene: ZNF259 zinc finger protein 259".

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References

Further reading

External links