PHF16

JADE3
Identifiers
Aliases	JADE3, JADE-3, PHF16, jade family PHD finger 3
External IDs	OMIM: 300618; MGI: 2148019; HomoloGene: 40981; GeneCards: JADE3; OMA:JADE3 - orthologs
Gene location (Human) Chr. X chromosome (human) Band Xp11.3 Start 46,912,276 bp End 47,061,242 bp
Gene location (Mouse) Chr. X chromosome (mouse) Band X|X A1.3 Start 20,291,927 bp End 20,386,178 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in corpus epididymis caput epididymis placenta right adrenal cortex seminal vesicula ganglionic eminence secondary oocyte left adrenal gland left adrenal cortex gonad Top expressed in tail of embryo superior cervical ganglion genital tubercle yolk sac medullary collecting duct cumulus cell primitive streak ovary islet of Langerhans urothelium More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding metal ion binding Cellular component histone acetyltransferase complex Biological process histone H4-K16 acetylation histone H4-K8 acetylation histone H4-K12 acetylation histone H3 acetylation histone H4-K5 acetylation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9767 382207 Ensembl ENSG00000102221 ENSMUSG00000037315 UniProt Q92613 Q6IE82 RefSeq (mRNA) NM_014735 NM_001077445 NM_001289684 NM_199317 RefSeq (protein) NP_001070913 NP_055550 NP_001276613 NP_955021 NP_001393168 NP_001393169 NP_001393170 Location (UCSC) Chr X: 46.91 – 47.06 Mb Chr X: 20.29 – 20.39 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Protein Jade-3 is a protein that in humans is encoded by the PHF16 gene.

This gene is part of a gene cluster on chromosome Xp11.23. The encoded protein contains a zinc finger motif often found in transcriptional regulators, however, its exact function is not known. Alternative splicing results in multiple transcript variants encoding the same protein.

Further reading

• Nagase T, Seki N, Ishikawa K, et al. (1997). "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain". DNA Res. 3 (5): 321–9, 341–54. doi:10.1093/dnares/3.5.321. PMID 9039502.
• Szelei J, Soto AM, Geck P, et al. (2000). "Identification of human estrogen-inducible transcripts that potentially mediate the apoptotic response in breast cancer". J. Steroid Biochem. Mol. Biol. 72 (3–4): 89–102. doi:10.1016/S0960-0760(00)00025-X. PMID 10775800. S2CID 25912630.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Tzouanacou E, Tweedie S, Wilson V (2003). "Identification of Jade1, a gene encoding a PHD zinc finger protein, in a gene trap mutagenesis screen for genes involved in anteroposterior axis development". Mol. Cell. Biol. 23 (23): 8553–2. doi:10.1128/MCB.23.23.8553-8562.2003. PMC 262661. PMID 14612400.
• Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome". Nature. 434 (7031): 325–37. Bibcode:2005Natur.434..325R. doi:10.1038/nature03440. PMC 2665286. PMID 15772651.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.

External links

• PHF16+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.