BRN-3

POU class 4 homeobox 2
POU class 4 homeobox 2
Identifiers
Symbol	POU4F2
Alt. symbols	BRN3B
NCBI gene	5458
HGNC	9219
OMIM	113725
RefSeq	NM_004575
UniProt	Q12837
Other data
Locus	Chr. 4 q31.22
Structures
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Structures	Swiss-model
Domains	InterPro

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Structures	Swiss-model
Domains	InterPro

POU class 4 homeobox 1
POU class 4 homeobox 1
Identifiers
Symbol	POU4F1
Alt. symbols	BRN3A
NCBI gene	5457
HGNC	9218
OMIM	601632
RefSeq	NM_006237
UniProt	Q01851
Other data
Locus	Chr. 13 q31.1
Structures
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Structures	Swiss-model
Domains	InterPro

POU class 4 homeobox 3

Identifiers

Symbol

POU4F3

Alt. symbols

BRN3C, DFNA15

Other data

Chr. 5 q32

Search for
Structures	Swiss-model
Domains	InterPro

BRN-3 is a group of related transcription factors in the POU family.^[1] They are also known as class 4 POU domain homeobox proteins.

There are three BRN-3 proteins encoded by the following genes:

BRN3A (POU4F1, POU4F1)
BRN3B (POU4F2, POU4F2)
BRN3C (POU4F3, POU4F3)

Nomenclature

The BRN or Brn prefix is an abbreviation for "brain"; the longer name is "Brain-specific homeobox". The name of the group may also be abbreviated as POU4, Pou4, POU IV, or POU-IV.

References

^ Xiang M, Zhou L, Macke JP, Yoshioka T, Hendry SH, Eddy RL, Shows TB, Nathans J (1995). "The Brn-3 family of POU-domain factors: primary structure, binding specificity, and expression in subsets of retinal ganglion cells and somatosensory neurons". J. Neurosci. 15 (7 Pt 1): 4762–85. doi:10.1523/JNEUROSCI.15-07-04762.1995. PMC 6577904. PMID 7623109.

External links

Transcription+Factor+Brn-3 at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article on a gene on human chromosome 13 is a stub. You can help Wikipedia by expanding it.

[pmid7623109-1] Xiang M, Zhou L, Macke JP, Yoshioka T, Hendry SH, Eddy RL, Shows TB, Nathans J (1995). "The Brn-3 family of POU-domain factors: primary structure, binding specificity, and expression in subsets of retinal ganglion cells and somatosensory neurons". J. Neurosci. 15 (7 Pt 1): 4762–85. doi:10.1523/JNEUROSCI.15-07-04762.1995. PMC 6577904. PMID 7623109.

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