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KDM5D

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KDM5D
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesKDM5D, HY, HYA, JARID1D, SMCY, lysine demethylase 5D
External IDsOMIM: 426000; MGI: 99780; HomoloGene: 55838; GeneCards: KDM5D; OMA:KDM5D - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001146705
NM_001146706
NM_004653

NM_011419

RefSeq (protein)

NP_001140177
NP_001140178
NP_004644

NP_035549

Location (UCSC)Chr Y: 19.7 – 19.74 MbChr Y: 0.9 – 0.96 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Lysine-specific demethylase 5D is an enzyme that in humans is encoded by the KDM5D gene.[5][6][7] KDM5D belongs to the alpha-ketoglutarate-dependent hydroxylases superfamily.

This gene encodes a protein containing zinc finger domains. A short peptide derived from this protein is a minor histocompatibility antigen which can lead to graft rejection of male donor cells in a female recipient.[7]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000012817Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000056673Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Froggatt P (Feb 1977). "The foundation of the "Inst" medical department and its association with the Belfast Fever Hospital". The Ulster Medical Journal. 45 (2): 107–45. PMC 2385577. PMID 795123.
  6. ^ Kent-First MG, Maffitt M, Muallem A, Brisco P, Shultz J, Ekenberg S, Agulnik AI, Agulnik I, Shramm D, Bavister B, Abdul-Mawgood A, VandeBerg J (October 1996). "Gene sequence and evolutionary conservation of human SMCY". Nature Genetics. 14 (2): 128–9. doi:10.1038/ng1096-128. PMID 8841177. S2CID 23054699.
  7. ^ a b "Entrez Gene: JARID1D jumonji, AT rich interactive domain 1D".

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.