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FOXN3

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FOXN3
Identifiers
AliasesFOXN3, C14orf116, CHES1, PRO1635, forkhead box N3
External IDsOMIM: 602628; MGI: 1918625; HomoloGene: 3809; GeneCards: FOXN3; OMA:FOXN3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005197
NM_001085471

NM_183186

RefSeq (protein)

NP_001078940
NP_005188

NP_899009

Location (UCSC)Chr 14: 89.12 – 89.62 MbChr 12: 99.16 – 99.53 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Forkhead box protein N3 is a protein that in humans is encoded by the FOXN3 gene.[5][6]

This gene is a member of the forkhead/winged helix transcription factor family. Checkpoints are eukaryotic DNA damage-inducible cell cycle arrests at G1 and G2. Checkpoint suppressor 1 suppresses multiple yeast checkpoint mutations including mec1, rad9, rad53 and dun1 by activating a MEC1-independent checkpoint pathway. Alternative splicing is observed at the locus, resulting in distinct isoforms.[6]

See also

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References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000053254Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000033713Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Pati D, Keller C, Groudine M, Plon SE (Jun 1997). "Reconstitution of a MEC1-independent checkpoint in yeast by expression of a novel human fork head cDNA". Mol Cell Biol. 17 (6): 3037–46. doi:10.1128/MCB.17.6.3037. PMC 232156. PMID 9154802.
  6. ^ a b "Entrez Gene: CHES1 checkpoint suppressor 1".

Further reading

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