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VN1R1

From Wikipedia, the free encyclopedia
VN1R1
Identifiers
AliasesVN1R1, V1RL1, VNR19I1, ZVNH1, ZVNR1, vomeronasal 1 receptor 1
External IDsOMIM: 605234; HomoloGene: 110801; GeneCards: VN1R1; OMA:VN1R1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_020633

n/a

RefSeq (protein)

NP_065684

n/a

Location (UCSC)Chr 19: 57.45 – 57.46 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Vomeronasal type-1 receptor 1 is a protein that in humans is encoded by the VN1R1 gene.[3][4]

Function

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Pheromones are chemical signals that elicit specific behavioral responses and physiologic alterations in recipients of the same species. The protein encoded by this gene is similar to pheromone receptors and is primarily localized to the olfactory mucosa. An alternate splice variant of this gene is thought to exist, but its full length nature has not been determined.[4]

Ligands

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References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000178201Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ Rodriguez I, Greer CA, Mok MY, Mombaerts P (September 2000). "A putative pheromone receptor gene expressed in human olfactory mucosa". Nature Genetics. 26 (1): 18–9. doi:10.1038/79124. PMID 10973240. S2CID 21063460.
  4. ^ a b "Entrez Gene: VN1R1 vomeronasal 1 receptor 1".
  5. ^ Shirokova E, Raguse JD, Meyerhof W, Krautwurst D. The human vomeronasal type-1 receptor family--detection of volatiles and cAMP signaling in HeLa/Olf cells. FASEB J. 2008 May;22(5):1416-25. doi:10.1096/fj.07-9233com PMID 18096815
  6. ^ Wallrabenstein I, Gerber J, Rasche S, Croy I, Kurtenbach S, Hummel T, Hatt H (June 2015). "The smelling of Hedione results in sex-differentiated human brain activity". NeuroImage. 113: 365–73. doi:10.1016/j.neuroimage.2015.03.029. PMID 25797832. S2CID 6526522.
  7. ^ Ouyang J, Bae H, Jordi S, Dao QM, Dossenbach S, Dehn S, Lingnau JB, Kanta De C, Kraft P, List B (Feb 2021). "The Smelling Principle of Vetiver Oil, Unveiled by Chemical Synthesis". Angew Chem Int Ed Engl. 60 (11): 5666–5672. doi:10.1002/anie.202014609. PMC 7986879. PMID 33315304. (reference 30)

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.