Selenophos

Selenophos^[1]
Names
	Preferred IUPAC name Se-[2-(Diethylamino)ethyl] O-ethyl ethylphosphonoselenoate
	Other names Seleno-VE
Identifiers
CAS Number	10161-84-9;
3D model (JSmol)	Interactive image;
ChemSpider	175244;
PubChem CID	202353;
CompTox Dashboard (EPA)	DTXSID00906396;
	InChI InChI=1S/C10H24NO2PSe/c1-5-11(6-2)9-10-15-14(12,8-4)13-7-3/h5-10H2,1-4H3 Key: QNGZOSUHNXJPIY-UHFFFAOYSA-N;
	SMILES CCN(CC)CC[Se]P(=O)(CC)OCC;
Properties
Chemical formula	C10H24NO2PSe
Molar mass	300.252 g·mol−1
Hazards
	Lethal dose or concentration (LD, LC):
LD50 (median dose)	21 μg/kg (mouse, subcutaneous)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Selenophos is an extremely potent organophosphate acetylcholinesterase inhibitor.^[3] It is the selenium analog of the VE nerve agent.

References

^ Nachmansohn, David (1 July 1969). "Proteins of Excitable Membranes". The Journal of General Physiology. 54 (1): 187–224. doi:10.1085/jgp.54.1.187. PMC 2225914. PMID 19873642.
^ Mager, Peter P. (1984). Multidimensional pharmacochemistry : design of safer drugs. Orlando: Academic Press. p. 354. ISBN 978-0-12-465020-6.
^ Akerfeldt, Stig.; Fagerlind, Lars. (January 1967). "Selenophosphorus Compounds as Powerful Cholinesterase Inhibitors". Journal of Medicinal Chemistry. 10 (1): 115–116. doi:10.1021/jm00313a032. PMID 6031689.

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