Dicyclohexyl phosphorofluoridate
Appearance
Names | |
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Other names
DCFP
Dicyclohexyl fluorophosphate TL-941 T-1840 | |
Identifiers | |
3D model (JSmol)
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ChemSpider | |
PubChem CID
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CompTox Dashboard (EPA)
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Properties | |
C12H22FO3P | |
Molar mass | 264.277 g·mol−1 |
Appearance | Colorless liquid |
Boiling point | 116 °C (241 °F; 389 K) |
Hazards | |
Occupational safety and health (OHS/OSH): | |
Main hazards
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Extremely toxic |
Lethal dose or concentration (LD, LC): | |
LC50 (median concentration)
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110 mg/m3 (inhalation, mice, 10 minutes) 110 mg/m3 (inhalation, rabbits, 10 minutes) 110 mg/m3 (inhalation, rats, 10 minutes) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Dicyclohexyl phosphorofluoridate (DCFP),[1] also known as TL-941 or T-1840,[2] is an extremely toxic organophosphorus compound with powerful anticholinesterase action. It's a colorless liquid that is extremely resistant to hydrolysis.[3] DCFP can be produced by reaction of cyclohexanol with phosphoryl dichloride fluoride.[2][3]
See also
[edit]References
[edit]- ^ BERRY, WK (October 1951). "The turnover number of cholinesterase". Biochemical Journal. 49 (5): 615–20. doi:10.1042/bj0490615. PMC 1197565. PMID 14886354.
- ^ a b Chemical Warfare Agents, and Related Chemical Problems. Parts I-II. 1958.
- ^ a b Some Aspects Of The Chemistry And Toxic Action Of Organic Compounds Containing Phosphorus And Fluorine. 1957.