TL-599
Appearance
(Redirected from SB-8)
Names | |
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Preferred IUPAC name
4-[(Dimethylcarbamoyl)oxy]-N,N,N-trimethyl-2-(propan-2-yl)anilinium iodide | |
Other names
SB-8
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Identifiers | |
3D model (JSmol)
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ChemSpider | |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C15H25IN2O2 | |
Molar mass | 392.281 g·mol−1 |
Hazards | |
Lethal dose or concentration (LD, LC): | |
LD50 (median dose)
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75 μg/kg (subcutaneous, mice)[1] 168 μg/kg (intraperitoneal, mice)[1] 75 μg/kg (mice, subcutaneous)[2] |
LDLo (lowest published)
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100 μg/kg (guinea pigs, subcutaneous)[1] |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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TL-599, also known as SB-8, is an extremely potent carbamate acetylcholinesterase inhibitor.[1][2]
See also
[edit]References
[edit]- ^ a b c d Chemical Warfare Agents, and Related Chemical Problems. Parts I-II. 1958.
- ^ a b Stevens, Joseph R.; Beutel, Ralph H. (January 1941). "Physostigmine Substitutes". Journal of the American Chemical Society. 63 (1): 308–311. doi:10.1021/ja01846a078.