EA-2192
(Redirected from Diisopropylaminoethyl methyl thiolophosphonate)
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| Names | |
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| Preferred IUPAC name
S-{2-[Di(propan-2-yl)amino]ethyl} methylphosphonothioate | |
| Other names
Diisopropylaminoethyl methyl thiolophosphonate
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| Identifiers | |
3D model (JSmol)
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| ChemSpider | |
PubChem CID
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| UNII | |
CompTox Dashboard (EPA)
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| Properties | |
| C9H22NO2PS | |
| Molar mass | 239.31 g·mol−1 |
| Appearance | White solid |
| Very soluble | |
| Hazards | |
| Occupational safety and health (OHS/OSH): | |
Main hazards
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Extremely toxic |
| Lethal dose or concentration (LD, LC): | |
LD50 (median dose)
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630 μg/kg (Rat, oral) 18 μg/kg (Rat, iv) 50 μg/kg (Mouse, iv) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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EA-2192 is an extremely toxic degradation product of the VX nerve agent.[1][2] It is a white solid that is very soluble and stable in water.
EA-2192 is an extremely potent acetylcholinesterase inhibitor. It is almost as toxic as VX itself.[3]
EA-2192 behaves similar to aged Soman as it is the dealkylated form of VX and cannot be reversed with common oxime reactivators.
See also
[edit]References
[edit]- ^ Ellison, D. Hank (2007). Handbook of chemical and biological warfare agents (2nd ed.). Boca Raton, Fla.: CRC. ISBN 9780849314346.
- ^ Hoenig, Steven L. (2007), Compendium of Chemical Warfare Agents, Springer, ISBN 978-0-387-34626-7
- ^ Munro, NB; Talmage, SS; Griffin, GD; Waters, LC; Watson, AP; King, JF; Hauschild, V (December 1999). "The sources, fate, and toxicity of chemical warfare agent degradation products". Environmental Health Perspectives. 107 (12): 933–74. doi:10.1289/ehp.99107933. PMC 1566810. PMID 10585900.
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