4-Methoxybutyrfentanyl

4-Methoxybutyrfentanyl
Clinical data
Other names	para-Methoxybutyryl fentanyl
Legal status
Legal status	CA: Schedule I; DE: NpSG (Industrial and scientific use only); UK: Class A; US: Schedule I; Illegal in Sweden;
Identifiers
	IUPAC name N-(4-Methoxyphenyl)-N-[1-(2-phenylethyl)-4-piperidinyl]-butanamide;
CAS Number	2088842-68-4;
PubChem CID	118796493;
ChemSpider	52085457;
UNII	Y72Z69R7K3;
CompTox Dashboard (EPA)	DTXSID401036781 ;
Chemical and physical data
Formula	C24H32N2O2
Molar mass	380.532 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCCC(=O)N(C1CCN(CC1)CCc2ccccc2)c3ccc(OC)cc3;
	InChI InChI=1S/C24H32N2O2/c1-3-7-24(27)26(21-10-12-23(28-2)13-11-21)22-15-18-25(19-16-22)17-14-20-8-5-4-6-9-20/h4-6,8-13,22H,3,7,14-19H2,1-2H3; Key:FNVSEQCPMXWQKG-UHFFFAOYSA-N;

4-Methoxybutyrfentanyl (also known as 4-MeO-BF) is an opioid analgesic that is an analog of butyrfentanyl and has been sold online as a designer drug.^[1]^[2]^[3]

Side effects

Side effects of fentanyl analogs are similar to those of fentanyl itself, which include itching, nausea and potentially serious respiratory depression, which can be life-threatening. Fentanyl analogs have killed hundreds of people throughout Europe and the former Soviet republics since the most recent resurgence in use began in Estonia in the early 2000s, and novel derivatives continue to appear.^[4]

Life-threatening adverse reactions have been observed.^[5]

Legal status

4-Methoxybutyrfentanyl is illegal in Sweden as of 26. January 2016.^[6]

4-Methoxybutyrfentanyl is a Schedule I controlled drug in the USA since 1. February 2018.^[7]

References

^ "4-MeO-Butyrfentanyl". Cayman Chemical.
^ "4-Methoxybutyrfentanyl". New Synthetic Drugs Database. Archived from the original on 2016-03-04. Retrieved 2016-02-06.
^ "ANALYTICAL REPORT - 4-MeO-BF" (PDF). European project RESPONSE.
^ Mounteney J, Giraudon I, Denissov G, Griffiths P (July 2015). "Fentanyls: Are we missing the signs? Highly potent and on the rise in Europe". The International Journal on Drug Policy. 26 (7): 626–31. doi:10.1016/j.drugpo.2015.04.003. PMID 25976511.
^ Helander A, Bäckberg M, Beck O (April 2016). "Intoxications involving the fentanyl analogs acetylfentanyl, 4-methoxybutyrfentanyl and furanylfentanyl: results from the Swedish STRIDA project". Clinical Toxicology. 54 (4): 324–32. doi:10.3109/15563650.2016.1139715. PMID 26850293. S2CID 41668288.
^ "31 nya ämnen kan klassas som narkotika eller hälsofarlig vara" (in Swedish). Folkhälsomyndigheten. November 2015.
^ "Schedules of Controlled Substances: Temporary Placement of Seven Fentanyl-Related Substances in Schedule I". Federal Register. 1 February 2018.

[1] "4-MeO-Butyrfentanyl". Cayman Chemical.

[2] "4-Methoxybutyrfentanyl". New Synthetic Drugs Database. Archived from the original on 2016-03-04. Retrieved 2016-02-06.

[3] "ANALYTICAL REPORT - 4-MeO-BF" (PDF). European project RESPONSE.

[4] Mounteney J, Giraudon I, Denissov G, Griffiths P (July 2015). "Fentanyls: Are we missing the signs? Highly potent and on the rise in Europe". The International Journal on Drug Policy. 26 (7): 626–31. doi:10.1016/j.drugpo.2015.04.003. PMID 25976511.

[5] Helander A, Bäckberg M, Beck O (April 2016). "Intoxications involving the fentanyl analogs acetylfentanyl, 4-methoxybutyrfentanyl and furanylfentanyl: results from the Swedish STRIDA project". Clinical Toxicology. 54 (4): 324–32. doi:10.3109/15563650.2016.1139715. PMID 26850293. S2CID 41668288.

[6] "31 nya ämnen kan klassas som narkotika eller hälsofarlig vara" (in Swedish). Folkhälsomyndigheten. November 2015.

[7] "Schedules of Controlled Substances: Temporary Placement of Seven Fentanyl-Related Substances in Schedule I". Federal Register. 1 February 2018.

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Side effects

Legal status

See also

References