Hexahydrocannabutol

Hexahydrocannabutol
Identifiers
	IUPAC name (6aR,10aR)-6,6,9-trimethyl-3-butyl-6a,7,8,9,10,10a-hexahydrobenzo[c]chromen-1-ol;
Chemical and physical data
Formula	C20H30O2
Molar mass	302.458 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCCCc1cc2OC(C)(C)[C@@H]3CCC(C)C[C@H]3c2c(O)c1;
	InChI InChI=1S/C20H30O2/c1-5-6-7-14-11-17(21)19-15-10-13(2)8-9-16(15)20(3,4)22-18(19)12-14/h11-13,15-16,21H,5-10H2,1-4H3/t13?,15-,16-/m1/s1; Key:UGRLMQVLYLFVDE-GNHXQJIDSA-N;

Hexahydrocannabutol (HHCB, HHC-B) is a semi-synthetic cannabinoid derivative, the hydrogenated derivative of tetrahydrocannabutol (THCB). It was first synthesised by Roger Adams in 1942 and produces only weak cannabinoid-like effects in animals.^[1] More recently it has been sold as an ingredient in grey-market cannabinoid products.^[2]

References

^ Adams R, Loewe S, Smith CM, McPhee WD (March 1942). "Tetrahydrocannabinol homologs and analogs with marihuana activity. XIII". Journal of the American Chemical Society. 64 (3): 694–697. doi:10.1021/ja01255a061.
^ "Classement des cannabinoïdes par puissance - la verte feuille" [Ranking of cannabinoids by potency - the green leaf]. la-verte-feuille.fr (in French). 17 October 2022. Archived from the original on 31 March 2023.

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[1] Adams R, Loewe S, Smith CM, McPhee WD (March 1942). "Tetrahydrocannabinol homologs and analogs with marihuana activity. XIII". Journal of the American Chemical Society. 64 (3): 694–697. doi:10.1021/ja01255a061.

[2] "Classement des cannabinoïdes par puissance - la verte feuille" [Ranking of cannabinoids by potency - the green leaf]. la-verte-feuille.fr (in French). 17 October 2022. Archived from the original on 31 March 2023.

[1]

[2]

See also

References