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Aknadinine

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Aknadinine
Names
Other names
4-demethylhasubanonine[1]
Identifiers
ChemSpider
UNII
Properties
C20H25NO5
Molar mass 359.42
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Aknadinine (also known as 4-demethylhasubanonine[1]) is an opioid alkaloid isolated from members of the genus Stephania (Stephania cepharantha[2] and Stephania hernandifolia.[3]). Structurally it is a member of the hasubanan family of alkaloids and features an isoquinoline substructure.

See also

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References

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  1. ^ a b Moza, B.K.; B. Bhaburi; D.K. Basu; J. Kunitomo; Y. Okamoto; E. Yuge; Y. Nagai; T. Ibuka (1970). "Constitution of three new alkaloids, aknadinine (4-demethylhasubanonine), aknadicine (4-demethylnorhasubanonine), and aknadilactam (4-demethyl-16-oxohasubanonine)". Tetrahedron. 26 (2): 427–433. doi:10.1016/S0040-4020(01)97839-1. ISSN 0040-4020.
  2. ^ He, L; Zhang, YH; Tang, LJ; Song, SH; Sun, QY (October 2010). "[Study on the alkaloids in the stems and leaves of Stephania cepharantha (II)]". Zhong Yao Cai (in Chinese). 33 (10): 1568–1570. PMID 21355192.
  3. ^ Kupchan, SM; Suffness, MI; White, DN; McPhail, AT; Sim, GA (1968). "The isolation and structural elucidation of 4-demethylhasubanonine, a new alkaloid from Stephania hernandifolia". Journal of Organic Chemistry. 33 (12): 4529–32. doi:10.1021/jo01276a052. PMID 5743784.