Jump to content

AN-788

From Wikipedia, the free encyclopedia

AN-788
Clinical data
Other namesAN788; NSD-788; NSD788; IP-2018; IP2018
Drug classMonoamine reuptake inhibitor; Serotonin–dopamine reuptake inhibitor
Identifiers
CAS Number

AN-788, also known as NSD-788 and IP-2018, is an experimental drug which was originated by NeuroSearch and is under development by Aniona and Saniona for the treatment of major depressive disorder.[1][2][3][4] It was also under development for anxiety disorders, but development for this indication was discontinued.[1] The drug acts as a serotonin–dopamine reuptake inhibitor (SDRI).[1][3][4] As of November of 2018, it is in an agreement for phase II clinical trials for major depressive disorder.[5] As of September 2022, no recent development has been reported for major depressive disorder, but the drug is now in phase 2 cinical trials for erectile dysfunction.[1]

See also

[edit]

References

[edit]
  1. ^ a b c d "Initiator Pharma". 8 November 2018.
  2. ^ "Delving into the Latest Updates on IP-2018 with Synapse". Synapse. 1 November 2024. Retrieved 2 November 2024.
  3. ^ a b Shao L, Li W, Xie Q, Yin H (February 2014). "Triple reuptake inhibitors: a patent review (2006 - 2012)". Expert Opinion on Therapeutic Patents. 24 (2): 131–154. doi:10.1517/13543776.2014.859676. PMID 24289044. S2CID 1825304.
  4. ^ a b Bang-Anderssen B, Bøgesø KP, Kehler J, Sánchez C (16 December 2016). "New Trends in Antidepresent Drug Research". In Ecker GF, Clausen RP, Sitte HH (eds.). Transporters as Drug Targets. Wiley. pp. 36–. ISBN 978-3-527-67951-5.
  5. ^ "Initiator Pharma signs option agreement for Phase 2 ready drug candidate". News Powered by Cision. 8 November 2018. Retrieved 2022-02-08.