Mofebutazone
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ECHA InfoCard | 100.016.947 |
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Formula | C13H16N2O2 |
Molar mass | 232.283 g·mol−1 |
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Mofebutazone (or monophenylbutazone) is a drug used for joint and muscular pain.[1][2] It is a 3,5-pyrazolinedione derivative.
The drug binds to plasma albumin and competes with drugs such as coumarin anticoagulants, indomethacin and glucocorticoids.
References
[edit]- ^ Kassem MA, Schulte KE (1984-07-01). "Pharmacokinetics of [4-14C] mofebutazone after oral administration in man". European Journal of Drug Metabolism and Pharmacokinetics. 9 (3): 223–227. doi:10.1007/BF03189645. PMID 6519123. S2CID 10985688.
- ^ Paradies HH (December 1987). "Structure of phenylbutazone and mofebutazone in the crystalline state and in solution". Journal of Pharmaceutical Sciences. 76 (12): 920–929. doi:10.1002/jps.2600761217. PMID 3440938.