Ibuprofen/paracetamol
Appearance
Combination of | |
---|---|
Ibuprofen | Nonsteroidal anti-inflammatory drug |
Paracetamol | Analgesic/antipyretic |
Clinical data | |
Trade names | Combogesic, Advil Dual Action with Acetaminophen, Ibupane |
Other names | Acetaminophen/ibuprofen |
AHFS/Drugs.com | Micromedex Detailed Consumer Information |
License data | |
Pregnancy category |
|
Routes of administration | By mouth |
ATC code | |
Legal status | |
Legal status | |
Identifiers | |
CAS Number | |
KEGG |
Ibuprofen/paracetamol, sold under the brand name Combogesic among others, is a fixed-dose combination of two medications, ibuprofen, a non-steroidal anti-inflammatory drug (NSAID); and paracetamol (acetaminophen), an analgesic and antipyretic.[6] It is available as a generic medication.[9][10][11]
Medical uses
[edit]Ibuprofen/paracetamol is indicated for the short term management of mild to moderate acute pain.[7]
There is evidence that paracetamol combined with ibuprofen provides pain relief better than either medication used alone.[12][13]
Adverse effects
[edit]Society and culture
[edit]Brand names
[edit]The combination is available as Combiflam,[11][14] Advil Dual Action with Acetaminophen,[15][16][17] Ibupane,[1] Nuromol and Combogesic.[7]
References
[edit]- ^ a b c "Ibupane" (PDF). TGA eBS. Archived from the original on 29 October 2020. Retrieved 29 April 2023.
- ^ "Nuromol Dual Action Pain Relief 200mg/500mg tablets - Summary of Product Characteristics (SmPC)". (emc). 15 June 2022. Archived from the original on 25 February 2023. Retrieved 24 February 2023.
- ^ "Nuromol Pain Relief 200mg/500mg Film Coated Tablets - Summary of Product Characteristics (SmPC)". (emc). 15 June 2022. Archived from the original on 25 February 2023. Retrieved 24 February 2023.
- ^ "Nuromol public assessment report". GOV.UK. 16 August 2021. Archived from the original on 25 February 2023. Retrieved 24 February 2023.
- ^ "Nuromol Dual Action Pain Relief 200mg/500mg tablets (ibuprofen/paracetamol): public consultation". GOV.UK. 13 May 2021. Archived from the original on 25 February 2023. Retrieved 24 February 2023.
- ^ a b "Advil Dual Action with Acetaminophen- ibuprofen, acetaminophen tablet, film coated". DailyMed. 1 December 2021. Archived from the original on 25 February 2023. Retrieved 25 February 2023.
- ^ a b c "Combogesic- acetaminophen and ibuprofen tablet, film coated". DailyMed. 9 March 2023. Archived from the original on 7 July 2024. Retrieved 6 July 2024.
- ^ "Combogesic IV- acetaminophen and ibuprofen injection injection". DailyMed. 29 April 2024. Archived from the original on 7 July 2024. Retrieved 6 July 2024.
- ^ "Competitive Generic Therapy Approvals". U.S. Food and Drug Administration (FDA). 29 June 2023. Archived from the original on 29 June 2023. Retrieved 29 June 2023.
- ^ "First Generic Drug Approvals 2023". U.S. Food and Drug Administration (FDA). 30 May 2023. Archived from the original on 30 June 2023. Retrieved 30 June 2023.
- ^ a b "Combiflam". drugs.com. Archived from the original on 5 February 2015. Retrieved 5 February 2015.
- ^ Ong CK, Seymour RA, Lirk P, Merry AF (April 2010). "Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain". Anesthesia and Analgesia. 110 (4): 1170–9. doi:10.1213/ANE.0b013e3181cf9281. PMID 20142348. S2CID 7948680.
- ^ Moore RA, Derry C (January 2013). "Efficacy of OTC analgesics". International Journal of Clinical Practice. Supplement. 67 (178): 21–5. doi:10.1111/ijcp.12054. PMID 23163544. S2CID 205184492.
- ^ "Combiflam". Sanofi India. 28 February 2023. Archived from the original on 3 March 2023. Retrieved 2 March 2023.
- ^ "Advil Dual Action: FDA-Approved Drugs". U.S. Food and Drug Administration (FDA). Archived from the original on 26 September 2020. Retrieved 28 February 2020.
- ^ "Drug Approval Package: Advil Dual Action with Acetaminophen". U.S. Food and Drug Administration (FDA). 31 March 2020. Archived from the original on 3 March 2023. Retrieved 2 March 2023.
- ^ "FDA approves GSK's Advil Dual Action with Acetaminophen for over-the-counter use in the United States" (Press release). GSK Consumer Healthcare. 28 February 2020. Archived from the original on 29 February 2020. Retrieved 28 February 2020 – via PR Newswire.