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Protein-coding gene in the species Homo sapiens
Keratin, type I cuticular Ha2 is a protein that in humans is encoded by the KRT32 gene .[ 5] [ 6] [ 7] [ 8]
The protein encoded by this gene is a member of the keratin gene family. As a type I hair keratin , it is an acidic protein which heterodimerizes with type II hair keratin to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q 21.2 and have the same direction of transcription.[ 8]
^ a b c GRCh38: Ensembl release 89: ENSG00000108759 – Ensembl , May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000046095 – Ensembl , May 2017
^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Rogers MA, Nischt R, Korge B, Krieg T, Fink TM, Lichter P, Winter H, Schweizer J (Nov 1995). "Sequence data and chromosomal localization of human type I and type II hair keratin genes". Exp Cell Res . 220 (2): 357–62. doi :10.1006/excr.1995.1326 . PMID 7556444 .
^ Rogers MA, Winter H, Langbein L, Krieg T, Schweizer J (Dec 1996). "Genomic characterization of the human type I cuticular hair keratin hHa2 and identification of an adjacent novel type I hair keratin gene hHa5" . J Invest Dermatol . 107 (4): 633–8. doi :10.1111/1523-1747.ep12584243 . PMID 8823373 .
^ Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW (Jul 2006). "New consensus nomenclature for mammalian keratins" . J Cell Biol . 174 (2): 169–74. doi :10.1083/jcb.200603161 . PMC 2064177 . PMID 16831889 .
^ a b "Entrez Gene: KRT32 keratin 32" .
Yu J, Yu DW, Checkla DM, et al. (1993). "Human hair keratins". J. Invest. Dermatol . 101 (1 Suppl): 56S–59S. doi :10.1111/1523-1747.ep12362635 (inactive 2024-04-03). PMID 7686952 . {{cite journal }}
: CS1 maint: DOI inactive as of April 2024 (link )
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein–protein interactions by mass spectrometry" . Mol. Syst. Biol . 3 (1): 89. doi :10.1038/msb4100134 . PMC 1847948 . PMID 17353931 .
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Langbein L, Rogers MA, Winter H, et al. (1999). "The catalog of human hair keratins. I. Expression of the nine type I members in the hair follicle" . J. Biol. Chem . 274 (28): 19874–84. doi :10.1074/jbc.274.28.19874 . PMID 10391933 .
Heid HW, Moll I, Franke WW (1988). "Patterns of expression of trichocytic and epithelial cytokeratins in mammalian tissues. I. Human and bovine hair follicles". Differentiation . 37 (2): 137–57. doi :10.1111/j.1432-0436.1988.tb00805.x . PMID 2456239 .