KIF13A

KIF13A
Identifiers
Aliases	KIF13A, RBKIN, bA500C11.2, kinesin family member 13A
External IDs	OMIM: 605433; MGI: 1098264; HomoloGene: 22589; GeneCards: KIF13A; OMA:KIF13A - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	17,987,635 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	46,929,867 bp
RNA expression pattern
	Top expressed in
	tendon of biceps brachii; ; Skeletal muscle tissue of rectus abdominis; ; Skeletal muscle tissue of biceps brachii; ; saphenous vein; ; internal globus pallidus; ; body of tongue; ; right ventricle; ; jejunum; ; synovial joint; ; nipple;
	Top expressed in
	muscle of thigh; ; soleus muscle; ; retinal pigment epithelium; ; atrium; ; myocardium of ventricle; ; skeletal muscle tissue; ; genital tubercle; ; temporal muscle; ; digastric muscle; ; triceps brachii muscle;
	More reference expression data
	n/a
Gene ontology
Molecular function	microtubule motor activity; nucleotide binding; microtubule binding; ATPase activity; protein binding; ATP binding;
Cellular component	cytoplasm; endosome; centrosome; Golgi apparatus; trans-Golgi network membrane; membrane; kinesin complex; Golgi membrane; microtubule organizing center; midbody; endosome membrane; microtubule; cytoskeleton; intracellular anatomical structure;
Biological process	plus-end-directed vesicle transport along microtubule; cytoskeleton-dependent intracellular transport; endosome to lysosome transport; cell division; melanosome organization; microtubule-based movement; vesicle cargo loading; protein transport; cell cycle; intracellular protein transport; Golgi to plasma membrane protein transport; regulation of cytokinesis;
	Sources:Amigo / QuickGO
Orthologs
	63971
	16553
	ENSG00000137177
	ENSMUSG00000021375
	Q9H1H9
	Q9EQW7
	NM_001105566; NM_001105567; NM_001105568; NM_001243423; NM_022113
	NM_010617
	NP_001099036; NP_001099037; NP_001099038; NP_001230352; NP_071396
	NP_034747
	Wikidata
View/Edit Human	View/Edit Mouse

Kinesin-like protein KIF13A is a protein that in humans is encoded by the KIF13A gene.^[5]^[6]

Interactions

KIF13A has been shown to interact with AP1B1.^[5]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000137177 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000021375 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b Nakagawa T, Setou M, Seog D, Ogasawara K, Dohmae N, Takio K, Hirokawa N (Jan 2001). "A novel motor, KIF13A, transports mannose-6-phosphate receptor to plasma membrane through direct interaction with AP-1 complex". Cell. 103 (4): 569–81. doi:10.1016/S0092-8674(00)00161-6. PMID 11106728. S2CID 18245989.
^ "Entrez Gene: KIF13A kinesin family member 13A".

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Hillier LD, Lennon G, Becker M, et al. (1997). "Generation and analysis of 280,000 human expressed sequence tags". Genome Res. 6 (9): 807–28. doi:10.1101/gr.6.9.807. PMID 8889549.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
De Graeve F, Bahr A, Chatton B, Kedinger C (2000). "A murine ATFa-associated factor with transcriptional repressing activity". Oncogene. 19 (14): 1807–19. doi:10.1038/sj.onc.1203492. PMID 10777215.
Jamain S, Quach H, Fellous M, Bourgeron T (2001). "Identification of the human KIF13A gene homologous to Drosophila kinesin-73 and candidate for schizophrenia". Genomics. 74 (1): 36–44. doi:10.1006/geno.2001.6535. PMID 11374900.
Chen D, Pajovic S, Duckett A, et al. (2002). "Genomic amplification in retinoblastoma narrowed to 0.6 megabase on chromosome 6p containing a kinesin-like gene, RBKIN". Cancer Res. 62 (4): 967–71. PMID 11861365.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi:10.1038/nature02055. PMID 14574404.
Colland F, Jacq X, Trouplin V, et al. (2004). "Functional proteomics mapping of a human signaling pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC 442148. PMID 15231748.
Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. S2CID 14294292.

This article on a gene on human chromosome 6 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000137177 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000021375 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11106728-5] Nakagawa T, Setou M, Seog D, Ogasawara K, Dohmae N, Takio K, Hirokawa N (Jan 2001). "A novel motor, KIF13A, transports mannose-6-phosphate receptor to plasma membrane through direct interaction with AP-1 complex". Cell. 103 (4): 569–81. doi:10.1016/S0092-8674(00)00161-6. PMID 11106728. S2CID 18245989.

[entrez-6] "Entrez Gene: KIF13A kinesin family member 13A".

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Interactions

References

Further reading