Isotetrahydrocannabinol
(Redirected from Iso-THC)
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| Formula | C21H30O2 |
| Molar mass | 314.469 g·mol−1 |
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Isotetrahydrocannabinol (iso-THC) is a phytocannabinoid similar in structure to cannabicitran which has been identified as a trace component of Cannabis, but is more commonly found as an impurity in synthetic THC which has been made from cannabidiol. iso-THC is present with other isomers with the double bond in a different position and the saturated dihydro derivative. iso-THC can be described as the upper cyclization product of CBD, while THC is the lower cyclization product of CBD. Its pharmacology has not been studied, though it is commonly found as a trace impurity in commercially marketed Δ8-THC products.[1][2][3][4]
See also
[edit]References
[edit]- ^ Marzullo P, Foschi F, Coppini DA, Fanchini F, Magnani L, Rusconi S, et al. (October 2020). "Cannabidiol as the Substrate in Acid-Catalyzed Intramolecular Cyclization". Journal of Natural Products. 83 (10): 2894–2901. doi:10.1021/acs.jnatprod.0c00436. PMC 8011986. PMID 32991167.
- ^ Nguyen GN, Jordan EN, Kayser O (June 2022). "Synthetic Strategies for Rare Cannabinoids Derived from Cannabis sativa". Journal of Natural Products. 85 (6): 1555–1568. doi:10.1021/acs.jnatprod.2c00155. PMID 35648593. S2CID 249234673.
- ^ Radwan MM, Wanas AS, Gul W, Ibrahim EA, ElSohly MA (April 2023). "Isolation and Characterization of Impurities in Commercially Marketed Δ8-THC Products". Journal of Natural Products. 86 (4): 822–829. doi:10.1021/acs.jnatprod.2c01008. PMID 36827690. S2CID 257183893.
- ^ Tanaka R, Kikura-Hanajiri R (June 2023). "Identification of hexahydrocannabinol (HHC), dihydro-iso-tetrahydrocannabinol (dihydro-iso-THC) and hexahydrocannabiphorol (HHCP) in electronic cigarette cartridge products". Forensic Toxicology. 42 (1): 71–81. doi:10.1007/s11419-023-00667-9. PMID 37365398. S2CID 259259903.
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