Draft:BW 247

BW 247
Identifiers
CAS Number	21912-88-9;
PubChem CID	89549;
ChemSpider	80819;
Chemical and physical data
Formula	C16H17N
Molar mass	223.319 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CNCC=C(C1=CC=CC=C1)C2=CC=CC=C2;

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Instructions · What links here · BW 247 (talk: + · bio) · (log) · Copyvios report · reFill · Citation Bot · (Search: Google, Wikipedia) · Submitted 2 days ago by Mo18ekula (talk: D · +) · Last edited 2 days ago by Wikishovel

BW-247 is an antidepressant.^[1]^[2]

BW-247 is a secondary amine, closely related in structure to the tricyclic antidepressants, which inhibits NA uptake in aortic strips^[3] and rat cerebral cortex slices.^[4] Unlike the tricyclic antidepressants, it is reported not to possess anticholinergic activity.^[5]

References

^ Castañer, J., Roberts, P. J. (1979). "BW-247". Drugs of the Future. 4 (2): 92. doi:10.1358/dof.1979.004.02.1002432.
^ Ankier, S. I. (1986). "Progress in Medicinal Chemistry". 4 Recent Progress in the Development of New Antidepressant Drugs. Vol. 23. Elsevier. pp. 121–185. doi:10.1016/S0079-6468(08)70342-4.
^ R.A. Maxwell, P.D. Keenan, E. Chaplin, B. Roth and S. Batimanglidj Eckhardt, J. Pharmacol. Exp. Ther., 166 (1969) 320.
^ A.I. Salama, J.R. Insalaco and R.A. Maxwell, J. Pharmacol. Exp. Ther., 178 (1971) 474.
^ J.W. Bridges, J.G. Dent and P. Johnson, Life Sci., 18 (1976) 97.

[1] Castañer, J., Roberts, P. J. (1979). "BW-247". Drugs of the Future. 4 (2): 92. doi:10.1358/dof.1979.004.02.1002432.

[2] Ankier, S. I. (1986). "Progress in Medicinal Chemistry". 4 Recent Progress in the Development of New Antidepressant Drugs. Vol. 23. Elsevier. pp. 121–185. doi:10.1016/S0079-6468(08)70342-4.

[3] R.A. Maxwell, P.D. Keenan, E. Chaplin, B. Roth and S. Batimanglidj Eckhardt, J. Pharmacol. Exp. Ther., 166 (1969) 320.

[4] A.I. Salama, J.R. Insalaco and R.A. Maxwell, J. Pharmacol. Exp. Ther., 178 (1971) 474.

[5] J.W. Bridges, J.G. Dent and P. Johnson, Life Sci., 18 (1976) 97.

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