Zytron
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Preferred IUPAC name
N-[(2,4-Dichlorophenoxy)-methoxyphosphinothioyl]propan-2-amine | |
Other names
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Identifiers | |
3D model (JSmol)
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ChemSpider | |
DrugBank | |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C10H14Cl2NO2PS | |
Molar mass | 314.16 g·mol−1 |
Appearance | Solid[1] |
Vapor pressure | 6.14x10-5 mm Hg[1] |
Hazards | |
Lethal dose or concentration (LD, LC): | |
LD50 (median dose)
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Zytron, also known as DMPA, is a chlorophenoxy herbicide.[1] It controls crabgrass and other weeds in turf preëmergently, and ants, chinch bugs and grubs.[2] It is used on baseball pitches in Australia.[3]
Zytron inhibits microtubule assembly, preventing mitosis. making it a Group 3 / D / K1, similar to dinitroanilines like trifluralin.[4] It was tested and commercially available in the US in 1959, and applied at 10-20 lbs per acre on turf,[5] a high rate compared to other herbicides.
Zytron disappears almost completely from the body within one hour of mammalian exposure.[2] It does not accumulate in soil and is non-harmful to microflora.[6] DMPA has in testing been applied at rates as high as 67 lbs per acre.[7]
Zytron may cause neurotoxicity in chickens. It is an organophosphorus ester, and other such chemicals are known to cause similar neurotoxicity. 100 mg/kg daily for 10 days was considered the minimum effective dose to observably alter hens' behaviour.[8]
Zytron has been sold under the tradenames "Dow Crabgrass Killer", "Dow 1329", "Dowco 118" and "T-H Crabgrass Killer."[9][10]
References
[edit]- ^ a b c d "Zytron". pubchem.ncbi.nlm.nih.gov.
- ^ a b St. John, Jr., Leigh E.; Lisk, Donald J. (January 1970). "Metabolic studies with Zytron herbicide in a lactating cow". Journal of Agricultural and Food Chemistry. 18 (1): 125–127. Bibcode:1970JAFC...18..125S. doi:10.1021/jf60167a031. PMID 5535663.
- ^ "2019 Baseball_Australia_Facility_Resource_2019.pdf" (PDF). Baseball Australia. 2019. Retrieved 5 November 2024.
- ^ "List of Herbicides Globally". www.weedscience.org.
- ^ Ahrens, J. F.; Olson, A. R. (March 1961). "Prevention and Control of Crabgrass in Lawns" (PDF). The Connecticut Agricultural Experiment Station (Bulletin 642). New Haven. Retrieved 5 November 2024.
- ^ Fields, M.L.; Hemphill, D.D. (14 March 1966). "Effect of Zytron and Its Degradation Products on Soil Microorganisms". Applied Microbiology. 14 (5). Department of Horticulture, University of Missouri: American Society for Microbiology: 724–731. doi:10.1128/am.14.5.724-731.1966. PMC 1058404. PMID 5970460.
- ^ Gibeault V. A.mSkogley, C.R., Effects of DMPA (Zytron) on Colonial Bentgrass, Kentucky Bluegrass, and Red Fescue Root Growth, uly, 1967
- ^ B. M. Francis, L. G. Hansen & R. L. Metcalf (1980) Neurotoxicity of halogenated o‐phenyl o‐alkyl alkylphosphonothioates, Journal of Environmental Science & Health Part B, 15:4, 313-331, DOI: 10.1080/03601238009372186
- ^ Macksam, William G.; Frost, Kenneth R.; Martin, Dean M. (1963). "Pre-Emergence Cr gence Crabgrass Contr ass Control" (PDF). South Dakota State University.
- ^ Briggs, Shirley A. (1992). BASIC GUIDE TO PESTICIDES -- Their Characteristics and Hazards. Taylor&Francis. ISBN 1-56032-253-5.