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Treatments for COVID-19: Current consensus

A note on WP:MEDRS: Per this Wikipedia policy, we must rely on the highest quality secondary sources and the recommendations of professional organizations and government bodies when determining the scientific consensus about medical treatments.

  1. Ivermectin: The highest quality sources (1 2 3 4) suggest Ivermectin is not an effective treatment for COVID-19. In all likelihood, ivermectin does not reduce all-cause mortality (moderate certainty) or improve quality of life (high certainty) when used to treat COVID-19 in the outpatient setting (4). Recommendations from relevant organizations can be summarized as: Evidence of efficacy for ivermectin is inconclusive. It should not be used outside of clinical trials. (May 2021, June 2021, June 2021, July 2021, July 2021) (WHO, FDA, IDSA, ASHP, CDC, NIH)
  2. Chloroquine & hydroxychloroquine: The highest quality sources (1 2 3 4) demonstrate that neither is effective for treating COVID-19. These analyses accounted for use both alone and in combination with azithromycin. Some data suggest their usage may worsen outcomes. Recommendations from relevant organizations can be summarized: Neither hydroxychloroquine nor chloroquine should be used, either alone or in combination with azithromycin, in inpatient or outpatient settings. (July 2020, Aug 2020, Sep 2020, May 2021) (WHO, FDA, IDSA, ASHP, NIH)
  3. Ivmmeta.com, c19ivermectin.com, c19hcq.com, hcqmeta.com, trialsitenews.com, etc: These sites are not reliable. The authors are pseudonymous. The findings have not been subject to peer review. We must rely on expert opinion, which describes these sites as unreliable. From published criticisms (1 2 3 4 5), it is clear that these analyses violate basic methodological norms which are known to cause spurious or false conclusions. These analyses include studies which have very small sample sizes, widely different dosages of treatment, open-label designs, different incompatible outcome measures, poor-quality control groups, and ad-hoc un-published trials which themselves did not undergo peer-review. (Dec 2020, Jan 2021, Feb 2021)

Last updated (diff) on 27 February 2023 by Sumanuil (t · c)


Origins of COVID-19: Current consensus

  1. There is no consensus on whether the lab leak theory is a "conspiracy theory" or a "minority scientific viewpoint". (RfC, February 2021)
  2. There is consensus against defining "disease and pandemic origins" (broadly speaking) as a form of biomedical information for the purpose of WP:MEDRS. However, information that already fits into biomedical information remains classified as such, even if it relates to disease and pandemic origins (e.g. genome sequences, symptom descriptions, phylogenetic trees). (RfC, May 2021)
  3. In multiple prior non-RFC discussions about manuscripts authored by Rossana Segreto and/or Yuri Deigin, editors have found the sources to be unreliable. Specifically, editors were not convinced by the credentials of the authors, and concerns were raised with the editorial oversight of the BioEssays "Problems & Paradigms" series. (Jan 2021, Jan 2021, Jan 2021, Feb 2021, June 2021, ...)
  4. The consensus of scientists is that SARS-CoV-2 is likely of zoonotic origin. (January 2021, May 2021, May 2021, May 2021, June 2021, June 2021, WP:NOLABLEAK (frequently cited in discussions))
  5. The March 2021 WHO report on the origins of SARS-CoV-2 should be referred to as the "WHO-convened report" or "WHO-convened study" on first usage in article prose, and may be abbreviated as "WHO report" or "WHO study" thereafter. (RfC, June 2021)
  6. The "manufactured bioweapon" idea should be described as a "conspiracy theory" in wiki-voice. (January 2021, February 2021, May 2021, May 2021, June 2021, June 2021, June 2021, June 2021, July 2021, July 2021, July 2021, August 2021)
  7. The scientific consensus (and the Frutos et al. sources ([1][2]) which support it), which dismisses the lab leak, should not be described as "based in part on Shi [Zhengli]'s emailed answers." (RfC, December 2021)
  8. The American FBI and Department of Energy finding that a lab leak was likely should not be mentioned in the lead of COVID-19 lab leak theory, because it is WP:UNDUE. (RFC, October 2023)
  9. The article COVID-19 lab leak theory may not go through the requested moves process between 4 March 2024 and 3 March 2025. (RM, March 2024)

Last updated (diff) on 15 March 2024 by Novem Linguae (t · c)


Lab leak theory sources

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List of good sources with good coverage to help expand. Not necessarily for inclusion but just for consideration. Preferably not articles that just discuss a single quote/press conference. The long-style reporting would be even better. Feel free to edit directly to add to the list. ProcrastinatingReader (talk) 17:39, 18 July 2021 (UTC)[reply]

Last updated by Julian Brown (talk) 23:43, 12 November 2023 (UTC) [reply]

[edit]  ·
Scholarship
For the relevant sourcing guideline, see WP:SCHOLARSHIP. For a database curated by the NCBI, see LitCoVID
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Journalism
For the relevant sourcing guideline, see WP:NEWSORG.
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Opinion-based editorials written by scientists/scholars
For the relevant sourcing guideline, see WP:RSOPINION.
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Opinion-based editorials written by journalists
For the relevant sourcing guideline, see WP:RSOPINION.
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Government and policy
Keep in mind, these are primary sources and thus should be used with caution!

References

Misinformation spread by Minister of AYUSH should also be considered misinformation spread by government

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If Minister of AYUSH Ministry has spread some misinformation then that should also be considered misinformation by Indian Government in my opinion as he is the head of Ministry of AYUSH. So, the following content should be added into the article:

Minister of State for AYUSH Shripad Naik claimed that an Ayurveda practitioner cured Prince Charles when he tested positive for the Covid-19. This claim was rubbished by United Kingdom officials.[1][2]

I would request other editors to present their opinion on it. Jasksingh (talk) 11:42, 29 May 2021 (UTC)[reply]

As no other editor has presented any opinion against it so I am adding the AYUSH Minister point. Jasksingh (talk) 18:08, 5 June 2021 (UTC)[reply]

About disinformation in Brazil

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It says that in spite of evidence of Chloroquine that it doesn't work. Bolsonaro continues recommending it. Well, this is not misinformation. As there is also plenty of evidence in support of it. Supporting the use of Chloroquine is not misinformation. This should be revised. 189.51.158.204 (talk) 15:31, 1 May 2022 (UTC)[reply]