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Merge proposal

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It seems to me that Acid-base imbalance should be merged into this article, as well as much of mixed disorder of acid-base balance. If no one objects, I'll do it. I'm posting word on those pages and the The Doctor's Mess. - Draeco (talk) 04:44, 21 August 2009 (UTC)[reply]

Done. Now that I've re-written the article, it seems natural to have an separate Acid-base imbalance article. I might split it out again at some point, but at any rate I think the current organization is much better than the previous 4 overlapping articles. - Draeco (talk) 20:55, 22 August 2009 (UTC)[reply]
Yeah, Arcadian was right when he split it last year. I'm doing it again. Sorry for being confusing - Draeco (talk) 16:23, 23 August 2009 (UTC)[reply]

Lead Infobox seems irrelevant

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The infobox "Blood gas, acid-base, & gas exchange terms" seems irrlevant to this article; I suggest remving it. Terry Dwyer (talk) 21:52, 21 June 2012 (UTC)[reply]

Done! Before I even read your comment.. ;-) Gorthian (talk) 08:15, 26 July 2013 (UTC)[reply]

Acid–base homeostasis

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The discussion in this section is fundamentally flawed on two counts

  1. The dissociation reaction HCO3- = CO32- + H+ is not mentioned. Although the concentration of carbonate at biological pH is rather low, it is not zero. See F Millero, T Graham, F Huang, D Pierrot; Marine Chem.,100,80 (2006) - stability constant values at ionic strength of sea-water.
  2. The Henderson-Hasselbalch equation is, strictly speaking, not applicable as the system also includes the equilibrium H2CO3 = CO2 + H2O (assuming that carbon dioxide remains in solution unless it is exhaled). Petergans (talk) 21:46, 11 January 2019 (UTC)[reply]

more needs to be said about the renal system

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The major product or respiration is CO2, which can be excreted as a gas. I think it might be worth mentioning in the "third level" discussed in the lead that the kidney is also essential for controlling the effects of the non-gaseous products, such as sulfate, on pH.--AJim (talk) 05:44, 23 August 2020 (UTC)[reply]

Acid-base balance redirect

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Hi, Quercus solaris, Acid-base balance links here, but Acid–base balance (and Acid–base equilibrium) w/ndash now links to Acid dissociation constant. I realized the at Kindey article where I meant to conform to ndash. Not sure which is better. I've been changing a lot of links, hopefully all ok. comp.arch (talk) 14:31, 2 April 2021 (UTC)[reply]

Minor discrepancy

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Acid–base_homeostasis#Imbalance gives the numbers 7.32 to 7.42 using a source from 1970, acidosis (at the end of the lede) 7.35 to 7.45 using a source from 2004. I don't have easy access to any of the two sources and the difference seems small, but something may have changed since 1970 (possibly the way it's measured) and the acidosis article explicitly names arterial blood (which may also be the cause of the discrepancy). Doesn't look a big deal, but it would be nice if someone could check it or knows what this is about. I already mentioned this on another talk page, but that one is going to be deleted, so I hope this won't be considered canvassing. 109.119.212.245 (talk) 19:25, 29 July 2022 (UTC)[reply]

This article mentions a typical difference between arterial and venous blood pH of 0.03, so that's probably it. Not sure if it's worth mentioning with this or another source. 109.119.212.245 (talk) 19:44, 29 July 2022 (UTC)[reply]

Ref dump from Dietary acid load

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There was some discussion at the deleted Dietary acid load article about saving some reliable sources for improving this article or creating a solid one about PRAL or a similar topic. The former article seemed to have some valid sources, but often didn't represent them fairly. I'm just dumping the refs from that article in case they may be useful, I don't mind if someone removes some of them from this list if they clearly are't considered WP:RSMED, for matters of WP:DUE or similar I would prefer to see a reply or eventually a comment added within the list. [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [11] [12] [13] [14] [15] [16] [17] [18] [19] [20] 176.247.167.221 (talk) 02:43, 4 August 2022 (UTC) 176.247.167.221 (talk) 02:43, 4 August 2022 (UTC)[reply]

References

  1. ^ "Potential renal acid load of foods and its influence on urine pH". J Am Diet Assoc. 95 (7): 791–7. July 1995. doi:10.1016/S0002-8223(95)00219-7. PMID 7797810. {{cite journal}}: Unknown parameter |authors= ignored (help)
  2. ^ Osuna-Padilla, I.A.; Leal-Escobar, G.; Garza-García, C.A.; Rodríguez-Castellanos, F.E. (July 2019). "Carga ácida de la dieta; mecanismos y evidencia de sus repercusiones en la salud". Nefrología. 39 (4): 343–354. doi:10.1016/j.nefro.2018.10.005.
  3. ^ Scialla, Julia J.; Appel, Lawrence J.; Astor, Brad C.; Miller, Edgar R.; Beddhu, Srinivasan; Woodward, Mark; Parekh, Rulan S.; Anderson, Cheryl A. M. (1 July 2011). "Estimated Net Endogenous Acid Production and Serum Bicarbonate in African Americans with Chronic Kidney Disease". Clinical Journal of the American Society of Nephrology. 6 (7): 1526–1532. doi:10.2215/CJN.00150111.
  4. ^ "Causal assessment of dietary acid load and bone disease: a systematic review & meta-analysis applying Hill's epidemiologic criteria for causality". Nutr J. 10: 41. 2011. doi:10.1186/1475-2891-10-41. PMC 3114717. PMID 21529374. {{cite journal}}: Unknown parameter |authors= ignored (help)CS1 maint: unflagged free DOI (link)
  5. ^ "Dietary acid load and the risk of cancer: a systematic review and dose-response meta-analysis of observational studies". Eur J Cancer Prev. March 2022. doi:10.1097/CEJ.0000000000000748. PMID 35307716. {{cite journal}}: Unknown parameter |authors= ignored (help)
  6. ^ "Dietary acid load, kidney function and risk of chronic kidney disease: A systematic review and meta-analysis of observational studies". Int J Vitam Nutr Res. 91 (3–4): 343–355. June 2021. doi:10.1024/0300-9831/a000584. PMID 30987546. S2CID 117716885. {{cite journal}}: Unknown parameter |authors= ignored (help)
  7. ^ "Dietary acid load and risk of hypertension: A systematic review and dose-response meta-analysis of observational studies". Nutr Metab Cardiovasc Dis. 29 (7): 665–675. July 2019. doi:10.1016/j.numecd.2019.03.009. PMID 31153745. S2CID 155711819. {{cite journal}}: Unknown parameter |authors= ignored (help)
  8. ^ "Elevated hypertension risk associated with higher dietary acid load: A systematic review and meta-analysis". Clin Nutr ESPEN. 33: 171–177. October 2019. doi:10.1016/j.clnesp.2019.05.020. PMID 31451256. S2CID 196562452. {{cite journal}}: Unknown parameter |authors= ignored (help)
  9. ^ "The Associations of Dietary Acid Load with Insulin Resistance and Type 2 Diabetes: A Systematic Review of Existing Human Studies". Recent Pat Food Nutr Agric. 10 (1): 27–33. 2019. doi:10.2174/2212798410666180924142222. PMID 30246649. S2CID 52334657. {{cite journal}}: Unknown parameter |authors= ignored (help)
  10. ^ "Dietary acid load and risk of type 2 diabetes: A systematic review and dose-response meta-analysis of prospective observational studies". Clin Nutr ESPEN. 23: 10–18. February 2018. doi:10.1016/j.clnesp.2017.12.005. PMID 29460782. {{cite journal}}: Unknown parameter |authors= ignored (help)
  11. ^ "Physiology, Acid Base Balance". StatPearls. StatPearls Publishing. 2022. PMID 29939584. {{cite book}}: Unknown parameter |authors= ignored (help)
  12. ^ "Nutritional disturbance in acid-base balance and osteoporosis: a hypothesis that disregards the essential homeostatic role of the kidney". Br J Nutr. 110 (7): 1168–77. October 2013. doi:10.1017/S0007114513000962. PMC 3828631. PMID 23551968. {{cite journal}}: Unknown parameter |authors= ignored (help)
  13. ^ "Diet-induced acidosis: is it real and clinically relevant?". Br. J. Nutr. 103 (8): 1185–94. April 2010. doi:10.1017/S0007114509993047. PMID 20003625. S2CID 4858964. {{cite journal}}: Unknown parameter |authors= ignored (help)
  14. ^ "Low-grade metabolic acidosis as a driver of chronic disease: a 21st century public health crisis". Open Heart. 8 (2). October 2021. doi:10.1136/openhrt-2021-001730. PMC 8549658. PMID 34702776. {{cite journal}}: Unknown parameter |authors= ignored (help)
  15. ^ Vormann, Jürgen; Werner, Tanja (August 2020). "Foreword to the contributions of the 3rd International Acid-Base Symposium, Smolenice Castle, Slovakia, 2018". European Journal of Clinical Nutrition. 74 (S1): 1–2. doi:10.1038/s41430-020-0682-8. eISSN 1476-5640. ISSN 0954-3007. S2CID 221382096.
  16. ^ Krause's Food & the Nutrition Care Process. L. Kathleen Mahan, Sylvia Escott-Stump, Janice L. Raymond, Marie V. Krause (13th ed.). Elsevier. 2012. pp. 803–806. ISBN 9781437722338.{{cite book}}: CS1 maint: others (link)
  17. ^ Krause's Food & the Nutrition Care Process. L. Kathleen Mahan, Janice L Raymond (14th ed.). Elsevier. 2016. pp. 703–706. ISBN 9780323340762.{{cite book}}: CS1 maint: others (link)
  18. ^ "KDOQI Clinical Practice Guideline for Nutrition in CKD: 2020 Update". Am J Kidney Dis. 76 (3 Suppl 1): S1–S107. September 2020. doi:10.1053/j.ajkd.2020.05.006. PMID 32829751. {{cite journal}}: Unknown parameter |authors= ignored (help)
  19. ^ joint FAO/WHO/UNU expert consultation (2007). "Chapter 13 Protein intake and health". Protein and amino acid requirements in human nutrition. pp. 223–233. hdl:10665/43411. ISBN 978-92-4-120935-9.
  20. ^ "Dietary, metabolic, physiologic, and disease-related aspects of acid-base balance: foreword to the contributions of the second International Acid-Base Symposium". J Nutr. 138 (2): 413S–414S. February 2008. doi:10.1093/jn/138.2.413S. PMID 18203912. {{cite journal}}: Unknown parameter |authors= ignored (help)
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