Glucose-6-phosphate exchanger SLC37A1 is a protein that in humans is encoded by the SLC37A1 gene.[5] SLC37A1 locates to the membrane of the endoplasmic reticulum (ER), and is a glucose 6-phosphate:inorganic phosphateantiporter, transporting glucose 6-phosphate from the cytoplasm into the lumen of the ER, while transporting phosphate in the opposite direction.[6]
Unlike the related SLC37A4 protein, SLC37A1 does not appear to be involved in blood glucosehomeostasis,[7] but does appear to regulate phosphate levels in the milk of cows, with flow-on effects on the volume of milk produced.[8]