Parathion S
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| Names | |
|---|---|
| Preferred IUPAC name
O,O-Diethyl S-(4-nitrophenyl) phosphorothioate | |
| Other names
S-Phenyl parathion
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| Identifiers | |
3D model (JSmol)
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| ChemSpider | |
PubChem CID
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CompTox Dashboard (EPA)
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| Properties | |
| C10H14NO5PS | |
| Molar mass | 291.26 g·mol−1 |
| Appearance | Pale yellow crystalline solid |
| Hazards | |
| Lethal dose or concentration (LD, LC): | |
LD50 (median dose)
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107 μg/kg (mice, intraperitoneal)[1] 4.41 mg/kg (rats, oral)[1] |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Parathion S is an organophosphate related to the organophosphate insecticide paraoxon and parathion. It's the structural isomer of parathion. Parathion S is a potent acetylcholinesterase inhibitor.[2][3]
See also
[edit]References
[edit]- ^ a b "ChemIDplus".
- ^ DIGGLE, WM; GAGE, JC (September 1951). "Cholinesterase inhibition in vitro by OO-diethyl O-p-nitrophenyl thiophosphate (parathion, E 605)". The Biochemical Journal. 49 (4): 491–4. doi:10.1042/bj0490491. PMC 1197537. PMID 14886312.
- ^ ALDRIDGE, WN; DAVISON, AN (December 1952). "The inhibition of erythrocyte cholinesterase by tri-esters of phosphoric acid. II. Diethyl p-nitrophenyl thionphosphate (E605) and analogues". The Biochemical Journal. 52 (4): 663–71. doi:10.1042/bj0520663. PMC 1198077. PMID 13018298.
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