Head and neck anatomy

This article describes the anatomy of the head and neck of the human body, including the brain, bones, muscles, blood vessels, nerves, glands, nose, mouth, teeth, tongue, and throat.

Structure

Bones

The head rests on the top part of the vertebral column, with the skull joining at C1 (the first cervical vertebra known as the atlas). The skeletal section of the head and neck forms the top part of the axial skeleton and is made up of the skull, hyoid bone, auditory ossicles, and cervical spine.

The skull can be further subdivided into:

the cranium (8 bones: frontal, 2-parietal, occipital, 2-temporal, sphenoid, ethmoid), and
the facial bones (14 bones: 2-zygomatic, 2-maxillary, 2-palatine, 2-nasal, 2-lacrimal, vomer, 2-inferior conchae, mandible).

The occipital bone joins with the atlas near the foramen magnum, a large hole (foramen) at the base of the skull. The atlas joins with the occipital condyle above and the axis below. The spinal cord passes through the foramen magnum.

Muscles

Group	Name	Nerve	Function
facial expression	Epicranius: Frontalis and Occipitalis	facial nerve	eyebrows and scalp
facial expression	Orbicularis oris	facial nerve	closes lips
facial expression	Zygomaticus major	facial nerve	smiling
facial expression	Zygomaticus minor	facial nerve	smiling
facial expression	Levator labii superioris	facial nerve	upper lip
facial expression	Levator labii superioris alaeque nasi	facial nerve	upper lip
facial expression	Depressor labii inferioris	facial nerve	lower lip
facial expression	Depressor anguli oris	facial nerve	frowning
facial expression	Platysma	facial nerve	frowning (during fear or shock)
facial expression	Buccinator	facial nerve	cheeks
facial expression	Mentalis	facial nerve	chin
facial expression	Platysma	facial nerve	frowning
facial expression	Risorius	facial nerve	mouth angle
facial expression	Orbicularis oculi	facial nerve	closes eye
facial expression	Nasalis	facial nerve	flare nostrils
facial expression	Corrugator supercilli	facial nerve	eyebrow
facial expression	Levator palpebrae superioris	oculomotor nerve	upper eyelid
chewing – lower mandible	Masseter	Trigeminal nerve	closing and protruding mandible,
chewing – lower mandible	Temporalis	Trigeminal nerve	elevates and controls side to side movement of mandible
chewing – lower mandible	Medial pterygoid	Trigeminal nerve	elevates mandible,
chewing – lower mandible	Lateral pterygoid	Trigeminal nerve	protracts mandible, opens mouth.
tongue – extrinsic	Genioglossus	hypoglossal nerve	protraction,
tongue – extrinsic	Styloglossus	hypoglossal nerve	elevation and retraction,
tongue – extrinsic	Hyoglossus	hypoglossal nerve	depresses tongue
tongue – extrinsic	Palatoglossus	Pharyngeal plexus, pharyngeal branch of vagus nerve	elevates tongue while swallowing
oral cavity floor	Digastric	Trigeminal nerve and Facial nerve	hyoid and mandible movement
oral cavity floor	Stylohyoid	Facial nerve	elevates hyoid
oral cavity floor	Mylohyoid	Trigeminal nerve	hyoid and mandible movement
oral cavity floor	Geniohyoid	Cervical nerve C-1	hyoid, tongue, and mandible movement
move head	Sternocleidomastoid	Accessory nerve	nodding and turning
move head	Semispinalis	dorsal rami of cervical nerves	extends head, supports turning
move head	Splenius capitis	dorsal rami of middle and lower cervical nerves	extend head, supports turning
move head	Longissimus capitis	dorsal rami of middle and lower cervical nerves	extends head, supports turning
move head	Rectus capitis posterior major	Suboccipital nerve C-1	extends head
move head	Rectus capitis posterior minor	Suboccipital nerve C-1	extends head

Skin

The head and neck is covered in skin and its appendages, termed the integumentary system. These include hair, sweat glands, sebaceous glands, and sensory nerves. The skin is made up of three microscopic layers: epidermis, dermis, and hypodermis. The epidermis is composed of stratified squamous epithelium and is divided into the following five sublayers or strata, listed in order from outer to inner:

Stratum corneum,
Stratum lucidum,
Stratum granulosum,
Stratum spinosum,
Stratum germinativum, also called stratum basale. The deepest layer is the miotic layer, stratum basale producing daughter cells by mitosis.

Mouth

The mouth, also called the oral cavity, is the entranceway into the digestive system containing both primary and accessory organs of digestion.

Teeth

Two rows of teeth are supported by facial bones of the skull, the maxilla above and the mandible below. Adults have 32 permanent teeth, and children have 20 deciduous teeth. There are various tooth shapes for different jobs. For example, when chewing, the upper teeth work together with the lower teeth of the same shape to bite, chew, and tear food. The names of these teeth are:

(1) Incisors, there are eight incisors located in the front of the mouth (four on the top and four on the bottom). They have sharp, chisel-shaped crowns that cut food.
(2) Cuspids (or canine tooth), the four cuspids are next to each incisor. Cuspids have a pointed edge to tear food.
(3) Premolars (or bicuspids), the four pairs of molars are located next to the cuspids. They crush and tear food.
(4) Molars, there are twelve molars, in sets of three, at the back of the mouth. They have wide surfaces that help to grind food.

The white visible part of a tooth is called the crown. The rounded upper projections of the back teeth are cusps. The hard white exterior covering of the tooth is the enamel. As the tooth tapers below the gumline, the neck is formed. Below the neck, holding the tooth into the bone, is the root of the tooth. The inner portions of the tooth consist of the dentin, a bonelike tissue, and the pulp. The pulp is a soft tissue area containing the nerve and blood vessels to nourish and protect the tooth, located within the pulp cavity.

A tooth sits in a specialized socket called the alveolus. The tooth is held in location by a periodontal ligament, with the assistance of cementum. Teeth are surrounded by gingiva, or gums, part of the periodontium, support tissue of oral cavity protection. The periodontium includes all of the support membranes of the dental structures surround and support the teeth such as the gums and the attachment surfaces and membranes. These include epithelial tissues (epithelium), connective tissues, (ligaments and bone), muscle tissue and nervous tissue.

Salivary glands

There are three sets of salivary glands: the parotid, the submandibular and the sublingual glands. The (exocrine) glands secrete saliva for proper mixing of food and provides enzymes to start chemical digestion. Saliva helps to hold together the formed bolus which is swallowed after chewing. Saliva is composed primarily of water, ions, salivary amylase, lysozymes, and trace amounts of urea.

Tongue

The tongue is a specialized skeletal muscle that is specially adapted for the activities of speech, chewing, developing gustatory sense (taste) and swallowing. The tongue contains two sets of muscles, the intrinsic- involved with shape of tongue, and the extrinsic- involved with tongue movement. It is attached to the hyoid bone. Terms meaning tongue include "glosso" (from Greek) and "lingual" (from Latin).

Nose

Microanatomy

The outer surfaces of the head and neck are lined by epithelium. The protective tissues of the oral cavity are continuous with the digestive tract are called mucosa or mucous membranes. The cells of the inner oral cavity are called the buccal mucosa.

The oral cavity is lined by a stratified squamous epithelium containing about three layers of cells.^{[citation needed]} They line the oral, nasal, and external auditory meatus, (ear), providing lubrication and protection against pathogens.

The lips are also protected by specialized sensory cells called Meissner's corpuscles.

Blood, lymph and nerve supply

Blood supply

Blood circulates from the upper systemic loop originating at the aortic arch, and includes: the brachiocephalic artery, left common carotid artery and left subclavian artery. The head and neck are emptied of blood by the subclavian vein and jugular vein.

Right side of neck dissection showing the brachiocephalic, right common carotid artery and its branches

The brachiocephalic artery or trunk is the first and largest artery that branches to form the right common carotid artery and the right subclavian artery. This artery provides blood to the right upper chest, right arm, neck, and head, through a branch called right vertebral artery. The right and left vertebral artery feed into the basilar artery and upward to the posterior cerebral artery, which provides most of the brain with oxygenated blood. The posterior cerebral artery and the posterior communicating artery are within the circle of Willis.

The left common carotid artery divides to form the: internal carotid artery (ICA) and an external carotid artery (ECA). The ICA supplies the brain. The ECA supplies the neck and face.

The left subclavian artery and the right subclavian artery, one on each side of the body form the internal thoracic artery, the vertebral artery, the thyrocervical trunk, and the costocervical trunk. The subclavian becomes the axillary artery at the lateral border of the first rib. The left subclavian artery also provides blood to the left upper chest and left arm.

Blood–brain barrier

The blood–brain barrier (BBB) is semi-permeable membrane that controls the capillary leak potential of the circulatory system. In most parts of the body, the smallest blood vessels, called capillaries, are lined with endothelial cells, which have small spaces between each individual cell so substances can move readily between the inside and the outside of the capillary. The endothelial cells of capillaries in the brain lack these spaces. Instead, the endothelial cells fit tightly together to create a tight junction which prevents substances from passing out of the bloodstream.

Specialized glial cells called astrocytes form a tight junction or protective barrier around brain blood vessels and may be important in the development of the BBB. Astrocytes may also be responsible for transporting ions (electrolytes) from the brain to the blood.

Venous drainage

Blood from the brain and neck flows from: (1) within the cranium via the internal jugular veins, a continuation of the sigmoid sinuses. The right and left external jugular veins drain from the parotid glands, facial muscles, scalp into the subclavian veins. The right and left vertebral veins drain the vertebrae and muscles into the right subclavian vein and into the superior vena cava, into the right atrium of the heart.

Lymphatic system

The lymphatic system drains the head and neck of excess interstitial fluid via lymph vessels or capillaries, equally into the right lymphatic duct and the thoracic duct.

Lymph nodes line the cervical spine and neck regions as well as along the face and jaw.

The tonsils also are lymphatic tissue and help mediate the ingestion of pathogens.

Tonsils in humans include, from superior to inferior: nasopharyngeal tonsils (also known as adenoids), palatine tonsils, and lingual tonsils.

Together this set of lymphatic tissue is called the tonsillar ring or Waldeyer's ring.

Nerve supply

The spinal nerves arise from the spinal column. The top section of the spine is the cervical section, which contains nerves that innervate muscles of the head, neck and thoracic cavity, as well as transmit sensory information to the CNS.

The cervical spine section contains seven vertebrae, C-1 through C-7, and eight nerve pairs, C-1 through C-8.

There is the formation of an extensive network of nerve groups or tracts attaching to the spinal cord in arrangements called rami or plexus.

The sensory branches of spinal nerves include: lesser occipital, C-2, great auricular, (C-2 and C-3); transverse cervical, C-2 and C-3; and supraclavicular, C-3 and C-4. These nerve groups transmit afferent (sensory) information from the scalp, neck, and shoulders to the brain.

The motor branches of spinal nerves include: ansa cervicalis, dividing into a superior root, C-1, and an inferior root, C-2 and C-3, and the phrenic nerve, C-3 to C-5, the segmental nerve branches, C-1 to C-5. These nerve groups transmit efferent nerve (motor) information from the brain to muscle groups of the scalp, neck, diaphragm (anatomy), and shoulders.

Additionally there are: (C5-C8, and T1) Brachial plexus, providing the entire nerve supply of the shoulder and upper limb; and includes supraclavicular branches (dorsal scapular, suprascapular, long thoracic) lateral cord (musculocutaneous, lateral antibrachial cutaneous, lateral head of median nerve), medial cord (ulnar, medial head of median nerve, medial antibrachial cutaneous, medial brachial cutaneous), posterior cord (axillary, radial), controlling the arm.

Damage to a person's spinal cord above C-5 may result in respiratory arrest and death if medicinal aid does not intervene.

Cranial nerves

Twelve pairs of cranial nerves emerge from the brain; these affect movements and sensation, and some special organs such as hearing of parts of the head and neck.

Function

Movements of the neck includes: flexion, extension, (nodding yes), and rotation (shaking head no).

The mouth has evolved to support chewing, (mastication) and swallowing (deglutition), and speech (phonation).

In addition to the teeth, other structures that aid chewing are the lips, cheeks, tongue, hard palate, soft palate, and floor of the mouth.

Endocrine glands

Several glands of the endocrine system are found within the head and neck. Endocrine means that the secretion is used within the body. Endocrine glands are termed as ductless and release their secretions directly into the blood. The endocrine system is under the direct supervision of the nervous system, using the negative feedback principal of homeostasis, to create hormones which act as chemical instant messengers.

The hypothalamus connects directly to the pituitary gland, both through the circulatory system and by direct connection of neurons. Also, within the cranium, the pineal gland, which attaches to the thalamus, controls the body's 24-hour rhythms circadian rhythm through the release of melatonin.

The pituitary gland secretes hormones that directly impact the body as well as hormones that indirectly control body functions because they activate other endocrine glands, such as the adrenal cortex (ACTH) and the thyroid gland (TSH). These two glands when stimulated by pituitary hormones then release their own hormones. The pituitary gland has two lobes, the anterior lobe and the posterior lobe. The anterior lobe secretes: growth hormone (GH), Luteinizing hormone (LH), Follicle stimulating hormone (FSH), Adrenocorticotropic hormone (ACTH), Thyroid-stimulating hormone (TSH), Prolactin (PRL), and the posterior lobe secretes: Antidieuretic hormone (ADH), and Oxytocin. There is an intermediate lobe, in adult humans it is just a thin layer of cells between the anterior and posterior pituitary, nearly indistinguishable from the anterior lobe. The intermediate lobe produces melanocyte-stimulating hormone (MSH).

In the neck are the thyroid and parathyroid glands, that secrete hormones that control metabolism and blood calcium levels. The four parathyroid glands are situated upon the back surface of the thyroid gland.

Respiratory system

The respiratory system begins in the head and neck, with air entering and leaving the body through the mouth and nose. The respiratory system involving the head and neck includes:

the nasal cavity for filtering, moistening, and warming the air
the pharynx or throat which is the combining point for respiratory and digestive system
the larynx or voice box containing the epiglottis
the trachea, or windpipe

These lead down into the lower respiratory tract. A critical junction between the respiratory and digestive systems is the epiglottis, a cartilage flap which shuts during swallowing to prevent aspiration. The epiglottis is normally open to support respiration and shuts during swallowing to prevent food and fluids from entering the trachea, activating the gag reflex or initiates the choking mechanism.

Central nervous system

The nervous system is composed of a central nervous system (CNS), brain and spinal cord, and the peripheral nervous system (PNS), cranial nerves and spinal nerves. The CNS is located within the dorsal cavity, and the PNS extends through the ventral cavity. The central nervous system provides control and coordination of all eleven body systems and utilizes the endocrine system to form hormone chemical messengers that transport through the blood to influence the activity of individual cells of the body and their associated tissues, organs and systems.

The CNS receives sensory (afferent) input from the PNS and directs the flow of information to association neurons (interneurons) to create chemical synapse responses which in turn cause the formation of motor (efferent nerve) responses to stimulus. Association neurons are located in the grey matter of the spinal cord and the brain.

The CNS is protected by the cranium, vertebral column, meninges, cerebrospinal fluid. The spinal cord is an extension of the brain. The spinal cord and the brain stem are joined at the base of the cranium at the foramen magnum. Most of the functions of the head and neck are directly influenced by the brain and transmitted to the PNS via the cranial nerves and spinal nerves of the cervical portion of the spine.

The PNS has two subdivisions

somatic nervous system (SNS). The SNS is associated with the voluntary control of body movements through the action of skeletal muscles, and also the reception of external stimuli.
the autonomic nervous system (ANS). The ANS is divided into subsystems: the sympathetic nervous system (SNS) and the parasympathetic (PNS) nervous systems. The SNS and PNS often have opposing effects in the same organs or physiological systems, and the ANS is a major factor in maintaining homeostasis.

Development

Bones

The facial bones usually form into pairs and then fuse together. As the cranium fuses, sutures are formed that resemble stitching between bone plates. In a newborn, the junction of the parietal bones with the frontal and occipital bones, form the anterior (front) and posterior (back) fontanelle, or soft spots. The separation of the cranial bone plates at time of birth facilitate passage of the head of the fetus through the mother's birth canal, or pelvic girdle. The parietal bones, and occipital bone can overlap each other in the birth canal, and form the unusual looking "cone head" appearance in a newborn when delivered in a natural, or vaginal, delivery.

Teeth

Humans normally will produce two sets of teeth called primary dentition, or deciduous teeth, and secondary dentition, or permanent teeth.

A tooth is the toughest known substance in the body exceeding bones in density and strength. Tooth enamel lends great strength to the tooth structure. The formation of a developing tooth includes the process of dentin formation, (see: dentinogenesis) and enamel formation, (see: amelogenesis). The tooth breaks through the gum into the mouth in a process called eruption. The formation of teeth begins in early fetal development and goes through six stages:

(1) initiation stage, 6th - 7th week
(2) bud stage, 8th wk
(3) cap stage, 9th-10 wk
(4) bell stage, 11th-12th wk
(5) apposition
(6) maturation stage

Clinical significance

Infection

Severe viral infections that affect the mouth, lips, or the oral cavity include: Oral cancer may have a viral link.

Minor viral infections include: Mumps is a viral infection of the parotid salivary glands. Chicken pox is a viral infection that can spread to the mouth.
Thrush (candidiasis) fungal infection. Tonsillitis is an inflammation of the tonsils and may cause a sore throat and fever. In chronic cases tonsillectomy may be required.

Infected teeth can on rare occasions cause infection to spread leading to cavernous sinus thrombosis, mediastinitis, or Ludwig's angina causing airway blockage.

Diseases may be transmitted by contact of the head, mouth, or body fluids, such as Herpes Simplex Virus Type I (HSV-1), Herpes Simplex Virus Type II (HSV-2) genital herpes, which may present as a lesion on the lips, and contactable via skin to skin contact

Other

Other diseases include: Gingivitis gum disease, periodontal disease, oral forms of syphilis and gonorrhea. Dental caries or dental cavities.
Temporomandibular joint diseases and disorders, commonly called TMJ.
Autoimmune diseases such as: Crohn's disease of the oral cavity, see reference below.

Careful observation of the oral cavity, teeth and gums may reveal indicators of other medical conditions. For example, a person suffering from the eating disorder, bulimia nervosa may show signs of excessive tooth and gum erosion.

Airway obstruction

The airway in the head and neck may be obstructed with swelling associated with an enlarged tongue (macroglossia), tonsils, with swelling associated with anaphylactic shock, angiooedema, or a foreign body.

Anaphylactic shock requires advanced medical care immediately; but other first aid measures include rescue breathing (part of CPR) and administration of epinephrine using an EpiPen for immediate administration of epinephrine (adrenaline) to reverse swelling and to keep the respiratory airway (trachea) open.

References

External links

v t e Joints and ligaments of the head and neck
Temporomandibular	Capsule Articular disk Lateral Temporomandibular ligament Medial Sphenomandibular ligament Stylomandibular ligament
Atlanto-occipital	capsule membranes (Anterior atlantooccipital membrane posterior atlantooccipital membrane)

v t e Muscles of the neck
Cervical	Platysma Sternocleidomastoid Longus capitis Longus colli Scalene anterior middle posterior Rectus capitis anterior muscle Rectus capitis lateralis muscle
Suboccipital	Rectus capitis posterior major minor Obliquus capitis inferior superior
Suprahyoid	Mylohyoid Stylohyoid Digastric Geniohyoid
Infrahyoid	Thyrohyoid Sternohyoid Sternothyroid Omohyoid
Pharynx	Pharyngeal constrictor superior middle inferior Stylopharyngeus Salpingopharyngeus
Larynx	Cricothyroid Cricoarytenoid posterior lateral Arytenoid oblique arytenoid aryepiglottic transverse arytenoid Thyroarytenoid vocal thyroepiglottic
Trachea	Trachealis
Fasciae	Deep cervical fascia Pretracheal fascia Prevertebral fascia Investing layer Carotid sheath Alar fascia Palatine aponeurosis Buccopharyngeal fascia Pharyngobasilar fascia Pharyngeal raphe

v t e Nerves of the cervical plexus
Superficial	C2 Lesser occipital C2–C3 Greater auricular Transverse cervical C3–C4 Supraclavicular
Deep	C1–C3 Ansa cervicalis superior root inferior root C3–C5 Phrenic

v t e Anatomy of the larynx
Cartilage	Epiglottis Vallecula Thyroid Adam's apple Cricoid Paired Arytenoid Vocal process Muscular process Corniculate Cuneiform
Ligaments and folds	Extrinsic ligaments Hyoepiglottic ligament Thyrohyoid membrane Lateral ligament Median ligament Thyroepiglottic ligament Cricotracheal ligament Intrinsic ligaments Quadrangular membrane Aryepiglottic Vestibular fold Cricothyroid ligament Vocal cords Histology
Laryngeal cavity	Laryngeal inlet Vestibule Rima vestibuli Ventricle Rima glottidis/Glottis Infraglottic cavity
Muscles	Cricothyroid Cricoarytenoid posterior lateral Arytenoid oblique arytenoid aryepiglottic transverse arytenoid Thyroarytenoid thyroepiglottic
Other	Cricothyroid joint Cricoarytenoid joint

v t e Anatomy of the mouth
Lip	Vermilion border Cupid's bow Frenulum of lower lip Labial commissure of mouth Philtrum White roll
Cheek	Buccal fat pad
Palate	Hard palate Soft palate Palatine raphe Incisive papilla
Gums	Interdental papilla Gingival sulcus Gingival margin Gingival fibers Junctional epithelium Mucogingival junction Sulcular epithelium Stippling Periodontium Cementum Philtrum Gingiva Periodontal ligament
Glands	Parotid gland duct Submandibular gland duct Sublingual gland duct Tubarial salivary gland
Teeth	see tooth anatomy
Tongue	Top Taste bud Median sulcus Terminal sulcus Foramen cecum Lingual tonsils Underside Frenulum Fimbriated fold Sublingual caruncle Glossoepiglottic folds Lingual septum
Back of mouth	Oropharynx fauces Plica semilunaris of the fauces Uvula Palatoglossal arch Palatopharyngeal arch Tonsillar fossa Palatine tonsil