Draft:Pramiverine
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| Clinical data | |
|---|---|
| Other names | Cintaverin, Monoverin, Propaminodiphene, Raptalgin, Sistalcin, Sistalgin, Syntaverin, EMD 9806, HSp 2986. |
| Identifiers | |
| CAS Number |
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| PubChem CID | |
| Chemical and physical data | |
| Formula | C21H27N |
| Molar mass | 293.454 g·mol−1 |
| 3D model (JSmol) | |
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Spasmolytic and cholinolytic analgesic.[1][2][3][4][5]
Having the amino group located outside of a 6 membered piperidine is certainly less common, and this method does not involve mustards. Budipine/Prodipine are almost identical in this regard. SIR 117 is also based on the same gross structure and heavily relies on the same basic synthesis technique as outlined at Cutter Laboratories in the 1960’s. Lednicer himself made many butyrophenones out of this exocyclic cyclohexamine atypical outlay that is different from piperidine. For example, U-32,802A is evident.
References
[edit]- ^ Morel CJ. Experimentelle Untersuchungen mit Pramiverin [Experimental studies on pramiverine (author's transl)]. Arzneimittelforschung. 1976 Apr;26(4b):699-702. German. PMID: 989018.
- ^ Enenkel HJ, Müller-Calgan H, Schorscher E. Zur cholinolytischen Wirkung von Pramiverin [On the cholinolytic activity of pramiverine]. Arzneimittelforschung. 1976 Apr;26(4b):690-6. German. PMID: 821493.
- ^ Niemann H, Jakob G. Oesophagusmanometrische Befunde beim Menschen nach intravenöser Applikation eines neuen Cholinolytikums (Pramiverin), von Atropin und von Scopolamin-butylbromid [Eosphagomanometric finding in man after intravenous administration of a new cholinolytic (pramiverine), atropine and scopolamine butylbromide]. Arzneimittelforschung. 1976 Apr;26(4b):728-30. German. PMID: 989022.
- ^ Chieri RA. Tierexperimentelle Untersuchungen auf spasmolytische und analgetische Wirkungen von Pramiverin, Metamizol sowie einer Kombination beider Substanzen [Animal experimental study on spasmolytic and analgesic activities of pramiverine, metamizole and their combination (author's transl)]. Arzneimittelforschung. 1976 Apr;26(4b):696-8. German. PMID: 989017.
- ^ Koch E. [Profile comment on clinical and experimental studies of pramiverine and pramiverine/metamizole (author's transl)]. Arzneimittelforschung. 1976;26(4b):686-9. PMID: 782469.