4-Methylcathinone
Tools
Actions
General
Print/export
In other projects
Appearance
From Wikipedia, the free encyclopedia
Stimulant designer drug
Legal status | |
---|---|
Legal status | |
Identifiers | |
| |
CAS Number |
|
PubChem CID | |
ChemSpider | |
UNII | |
CompTox Dashboard (EPA) | |
Chemical and physical data | |
Formula | C10H13NO |
Molar mass | 163.220 g·mol−1 |
3D model (JSmol) | |
| |
|
4-Methylcathinone (also known as Nor-Mephedrone, 4-MC and NSC-60487), is a stimulant drug of the cathinone chemical class. It is a metabolite of the better known drug mephedrone (4-methylmethcathinone).[1][2][3][4]
4-Methylcathinone displays a 2.4-fold selectivity to promote monoamine release via DAT over SERT as opposed to 309-fold selectivity for cathinone.[5] It also releases norepinephrine.[5]
See also
[edit]References
[edit]- ^ "nor-Mephedrone". Cayman Chemical. Retrieved 27 June 2015.
- ^ Meyer MR, Wilhelm J, Peters FT, Maurer HH (June 2010). "Beta-keto amphetamines: studies on the metabolism of the designer drug mephedrone and toxicological detection of mephedrone, butylone, and methylone in urine using gas chromatography-mass spectrometry". Analytical and Bioanalytical Chemistry. 397 (3): 1225–33. doi:10.1007/s00216-010-3636-5. PMID 20333362. S2CID 21471611.
- ^ Pedersen AJ, Reitzel LA, Johansen SS, Linnet K (June 2013). "In vitro metabolism studies on mephedrone and analysis of forensic cases". Drug Testing and Analysis. 5 (6): 430–8. doi:10.1002/dta.1369. PMID 22573603.
- ^ Dargan PI, Sedefov R, Gallegos A, Wood DM (July–August 2011). "The pharmacology and toxicology of the synthetic cathinone mephedrone (4-methylmethcathinone)". Drug Testing and Analysis. 3 (7–8): 454–63. doi:10.1002/dta.312. PMID 21755604.
- ^ a b Hutsell BA, Baumann MH, Partilla JS, Banks ML, Vekariya R, Glennon RA, Negus SS (February 2016). "Abuse-related neurochemical and behavioral effects of cathinone and 4-methylcathinone stereoisomers in rats". European Neuropsychopharmacology. 26 (2): 288–297. doi:10.1016/j.euroneuro.2015.12.010. PMC 5331761. PMID 26738428.
Phenylalkyl- amines (other than cathinones) |
|
---|---|
Cyclized phenyl- alkylamines | |
Cathinones | |
Tryptamines | |
Chemical classes |
Phenethylamines |
|
---|---|
Amphetamines |
|
Phentermines |
|
Cathinones |
|
Phenylisobutylamines | |
Phenylalkylpyrrolidines | |
Catecholamines (and close relatives) |
|
Miscellaneous |
|
This drug article relating to the nervous system is a stub. You can help Wikipedia by expanding it. |
Hidden categories:
- Articles with short description
- Short description is different from Wikidata
- Articles without EBI source
- Chemical pages without DrugBank identifier
- Articles without KEGG source
- Multiple chemicals in Infobox drug
- Chemicals using indexlabels
- Chemical articles with multiple CAS registry numbers
- Drugs missing an ATC code
- Articles containing unverified chemical infoboxes
- All stub articles