4α-Methylfecosterol
Appearance
(Redirected from 4α-methylfecosterol)
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IUPAC name
4α-Methyl-5α-campestane-8,24(241)-dien-3β-ol
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Systematic IUPAC name
(1R,3aR,5aS,6S,7S,9aS,11aR)-6,9a,11a-Trimethyl-1-[(2R)-6-methyl-5-methylideneheptan-2-yl]-2,3,3a,4,5,5a,6,7,8,9,9a,10,11,11a-tetradecahydro-1H-cyclopenta[a]phenanthren-7-ol | |
Identifiers | |
3D model (JSmol)
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ChEBI | |
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KEGG | |
PubChem CID
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CompTox Dashboard (EPA)
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Properties | |
C29H48O | |
Molar mass | 412.702 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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4α-Methylfecosterol is a metabolic intermediate of sterols made by certain fungis, can be converted to 24-Methylenelophenol by enzyme HYD1, or undergo 4-demethylation to fecosterol.[1][2]
References
[edit]- ^ Kuchta, T; Bartková, K; Kubinec, R (30 November 1992). "Ergosterol depletion and 4-methyl sterols accumulation in the yeast Saccharomyces cerevisiae treated with an antifungal, 6-amino-2-n-pentylthiobenzothiazole". Biochemical and Biophysical Research Communications. 189 (1): 85–91. doi:10.1016/0006-291x(92)91529-y. PMID 1449509.
- ^ Kuchta, T; Léka, C; Farkas, P; Bujdáková, H; Belajová, E; Russell, NJ (July 1995). "Inhibition of sterol 4-demethylation in Candida albicans by 6-amino-2-n-pentylthiobenzothiazole, a novel mechanism of action for an antifungal agent". Antimicrobial Agents and Chemotherapy. 39 (7): 1538–41. doi:10.1128/aac.39.7.1538. PMC 162777. PMID 7492100.