The song was released through the iTunes Store on March 27, 2007. The song debuted at number 51 on the US Hot R&B/Hip-Hop Songs chart and has since peaked at number 26 on the chart. It debuted on the US Billboard Hot 100 on the issue date of April 14, 2007, at number 75, and has since peaked at number 28 on the chart.
VIBE selected Lil Wayne's guest appearance in "We Takin' Over" to be his best of 2007, ranking the song at No. 1 on their list of the 77 best Lil Wayne songs and appearances.[1]
Lil' Wayne recorded a remix/freestyle of 'We Takin' Over', known to some as 'My Daddy' for his mixtape, Da Drought 3.
Nicki Minaj also recorded a remix/freestyle of 'We Takin' Over', titled 'Playtime Is Over' for her mixtape, Playtime Is Over. Female rappers Trina, Remy Ma and Jacki-O, and singers Lil' Mo, and DJ Lazy K recorded a remix for Remy Ma's mixtape, Shesus Khryst, which was also featured on Trina's mixtape, Rockstarr Royalty, albeit slightly edited. Flo Rida also has a remix called the "Poe Boy Remix" from his Mr. Birthday Man mixtape. It features Brisco, Triple C's, and Ashley Ross.
The song was also re-released in 2011 as a single by singer Akon, who was also featured on the original release in 2007.
