Jack Spilsbury of We Rave You wrote that, the song "featuring heavy and power synths and incredible vocals and rapping from Rick Ross and Rich Brian".[3] It is written in the key of D major, with a tempo of 104 beats per minute.[4]
Brian Bonavoglia of DJ Times described the track "as an exhilarating anthem that sees the worlds of hip-hop and menacing mid-tempo combine into one making for one adrenaline-pumping listening experience".[5] Jason Heffler of EDM.com commented that "Run It" as "a heart-racing banger fit for the suspenseful action sequences of a tentpole Marvel film".[6] Oliver Tryon of Cultr praised the song "[is] perfect for the movie, a hard hitting, energetic track that [you] can envision being placed throughout a car chase or the like".[7]
The music video was released on 14 September 2021, which appeared in the film Shang-Chi and the official soundtrack, and also starred the film's lead actor, Simu Liu. It showcases Liu "battle it out on the dance floor with the DJ Snake".[8]
ESPN announced that the song was used in the background music for the 2021-22 college football season and serve as the anthem for the coverage, which started on 28 August.[10]
