User talk:Medtrans el 01
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[edit]Vaccine description | |
---|---|
Target | influenza virus |
Clinical data | |
Trade names | Fluarix, Fluzone, other |
AHFS/Drugs.com | Monograph |
Routes of administration | IM, intranasal |
ATC code | |
Legal status | |
Legal status |
|
Τα εμβόλια της γρίπης, επίσης γνωστά ως αντιγριπικά εμβόλια, είναι εμβόλια που προστατεύουν από τη γρίπη.[2] A new version of the vaccine is developed twice a year as the influenza virus rapidly changes.[2] While their effectiveness varies from year to year, most provide modest to high protection against influenza.[2][3] They decrease the number of missed days of work by a half day on average.[4] Vaccinating children may protect those around them[2] but the effectiveness of the vaccine in those over 65 years old is unknown because the evidence for this group is poor.[5][6]
Both the World Health Organization and Centers for Disease Control and Prevention recommends nearly all people over the age of 6 months get the vaccine yearly.[2][7] This is especially true for pregnant women, children between six months and five years of age, those with other health problems, Native Americans, and those who work in healthcare.[1][2]
The vaccines are generally safe. In children fever occurs in between 5 to 10%, as may muscle pains or feeling tired. In certain years, the vaccine causes Guillain-Barre syndrome in older people in about one per million doses. It should not be given to those with severe allergies to eggs or to previous versions of the vaccine. The vaccines come in both inactive and weakened viral forms. The inactive version should be used for those who are pregnant. They come in forms that are injected into a muscle, sprayed into the nose, or injected into the middle layer of the skin.[2]
Vaccination against influenza began in the 1930s with large scale availability in the United States beginning in 1945.[8][9] It is on the World Health Organization's List of Essential Medicines, the most important medications recommended for a basic health system.[10] The wholesale price is about 5.25 USD per dose as of 2014.[11] In the United States it costs less than 25 USD.[12]
References
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- ^ a b "Influenza Virus Vaccine Inactivated". The American Society of Health-System Pharmacists. Retrieved Jan 8, 2015.
- ^ a b c d e f g "Vaccines against influenza WHO position paper – November 2012" (PDF). Wkly Epidemiol Rec. 87 (46): 461–76. Nov 23, 2012. PMID 23210147.
- ^ Manzoli L; Ioannidis JP; Flacco ME; De Vito C; Villari P (July 2012). "Effectiveness and harms of seasonal and pandemic influenza vaccines in children, adults and elderly: a critical review and re-analysis of 15 meta-analyses". Hum Vaccin Immunother. 8 (7): 851–62. doi:10.4161/hv.19917. PMC 3495721. PMID 22777099.
- ^ Jefferson, T; Di Pietrantonj, C; Rivetti, A; Bawazeer, GA; Al-Ansary, LA; Ferroni, E (13 March 2014). "Vaccines for preventing influenza in healthy adults". The Cochrane database of systematic reviews. 3: CD001269. doi:10.1002/14651858.CD001269.pub5. PMID 24623315.
- ^ Osterholm, MT; Kelley, NS; Sommer, A; Belongia, EA (Jan 2012). "Efficacy and effectiveness of influenza vaccines: a systematic review and meta-analysis". The Lancet. Infectious diseases. 12 (1): 36–44. doi:10.1016/S1473-3099(11)70295-X. PMID 22032844.
- ^ Jefferson, T; Di Pietrantonj, C; Al-Ansary, LA; Ferroni, E; Thorning, S; Thomas, RE (Feb 17, 2010). "Vaccines for preventing influenza in the elderly". The Cochrane database of systematic reviews (2): CD004876. doi:10.1002/14651858.CD004876.pub3. PMID 20166072.
- ^ "Who Should Get Vaccinated Against Influenza". U.S. Centers for Disease Control and Prevention. 2015-11-04. Retrieved 2015-12-08.
- ^ Compans, Richard W. (2009). Vaccines for pandemic influenza. Dordrecht: Springer. p. 49. ISBN 9783540921653.
- ^ Vaccine Analysis: Strategies, Principles, and Control. Springer. 2014. p. 61. ISBN 9783662450246.
- ^ "19th WHO Model List of Essential Medicines (April 2015)" (PDF). WHO. April 2015. Retrieved May 10, 2015.
- ^ "Vaccine, influenza". International Drug Price Indicator Guide. Retrieved 6 December 2015.
- ^ Hamilton, Richart (2015). Tarascon Pocket Pharmacopoeia 2015 Deluxe Lab-Coat Edition. Jones & Bartlett Learning. p. 314. ISBN 9781284057560.