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Thymidylate 5'-phosphatase

From Wikipedia, the free encyclopedia
thymidylate 5′-phosphatase
Identifiers
EC no.3.1.3.35
CAS no.9026-80-6
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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NCBIproteins

The enzyme thymidylate 5′-phosphatase (EC 3.1.3.35) catalyzes the reaction

thymidylate + H2O thymidine + phosphate

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name is thymidylate 5′-phosphohydrolase. Other names in common use include thymidylate 5′-nucleotidase, deoxythymidylate 5′-nucleotidase, thymidylate nucleotidase, deoxythymidylic 5′-nucleotidase, deoxythymidylate phosphohydrolase, and dTMPase.

References

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  • Aposhian HV, Tremblay GY (1966). "Deoxythymidylate 5′-nucleotidase. Purification and properties of an enzyme found after infection of Bacillus subtilis with phage SP5C". J. Biol. Chem. 241 (21): 5095–101. PMID 4958986.