Talk:Two-component regulatory system

Microbiology Mid‑importance

	This article is within the scope of WikiProject Microbiology, a collaborative effort to improve the coverage of Microbiology on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.MicrobiologyWikipedia:WikiProject MicrobiologyTemplate:WikiProject MicrobiologyMicrobiology articles
Mid	This article has been rated as Mid-importance on the project's importance scale.

Molecular Biology: MCB / Cell Signaling

	This article is within the scope of WikiProject Molecular Biology, a collaborative effort to improve the coverage of Molecular Biology on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.Molecular BiologyWikipedia:WikiProject Molecular BiologyTemplate:WikiProject Molecular BiologyMolecular Biology articles
???	This article has not yet received a rating on the importance scale.
	This article is supported by the Molecular and Cell Biology task force (assessed as Mid-importance).
	This article is within the scope of the Cell Signaling task force, a task force which is currently considered to be inactive.

Change name of article to "Two-component regulatory system"

The mode of signal transduction described in this article is known as "two-component regulatory system(s)," not "two-component regulation system(s)." The title needs to be corrected. NighthawkJ (talk) 19:56, 21 April 2008 (UTC)[reply]

Since there are no objections, I went ahead and made the change. NighthawkJ (talk) 16:45, 3 September 2008 (UTC)[reply]

I think this is stated in the literature as "Two-component signal transduction system" (see titles of references). --kupirijo (talk) 19:40, 3 September 2018 (UTC)[reply]

Sensorcomponent

Is the sensor in two-component regulation really always a histidin kinase? Where is that information found? Akita86 (talk) 14:11, 28 January 2009 (UTC)[reply]

I haven't heard of any other type of kinase that mediates this function. Most of the references in the article have implicated Histidine kinase as the sensor in these systems. If you come across any other type of kinase please let me know so I can include it in the article for completeness.Lilypink (talk) 18:09, 28 January 2009 (UTC)[reply]

Two-component systems are by definition systems containing a histidine kinase and a response regulator. However, eukaryotic two-component systems almost exclusively diverge from histidine kinases. An example are the phytochromes of plants, which are HK homologues which have serine/threonine kinase activity. Silasmellor (talk) 20:51, 2 April 2010 (UTC)[reply]

Figure of His Kinase A (phospho-acceptor) domain

Figure of His Kinase A (phospho-acceptor) domain makes no sense as there are shown 21 unaligned NMR models (of the same domain). In fact, the domain is much more simple - it is a 4-helical coiled coil. — Preceding unsigned comment added by 147.173.212.105 (talk) 13:46, 14 February 2013 (UTC)[reply]