Talk:Detyrosination
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- What I think should be changed:
It is a slow acting enzyme that uses polymeric tubulin as a substrate.
- Why it should be changed:
There are three new papers that identify this enzyme, two in 2017, and one in 2022. For two of those I am co-author. However, my 2-17 edit was considered spam by MrOllie and removed. Thus now only one reference remains, and that is wrong formatted. The correct text is:
The identity of the tubulin detyrosinase enzymes, was revealed first in 2017 (the two vasohibins, VASH1 and VASH2, supported by the SVBP protein) and then later in 2022 (a new enzyme, called MATCAP).
- References supporting the possible change (format using the "cite" button):
Perrakis (talk) 16:01, 30 November 2022 (UTC)
References
- ^ Nieuwenhuis J, Adamopoulos A, Bleijerveld OB, Mazouzi A, Stickel E, Celie P, Altelaar M, Knipscheer P, Perrakis A, Blomen VA, Brummelkamp TR. Vasohibins encode tubulin detyrosinating activity. Science. 2017 Dec 15;358(6369):1453-1456. doi: 10.1126/science.aao5676. Epub 2017 Nov 16. PMID: 29146869.
- ^ Aillaud C, Bosc C, Peris L, Bosson A, Heemeryck P, Van Dijk J, Le Friec J, Boulan B, Vossier F, Sanman LE, Syed S, Amara N, Couté Y, Lafanechère L, Denarier E, Delphin C, Pelletier L, Humbert S, Bogyo M, Andrieux A, Rogowski K, Moutin MJ. Vasohibins/SVBP are tubulin carboxypeptidases (TCPs) that regulate neuron differentiation. Science. 2017 Dec 15;358(6369):1448-1453. doi: 10.1126/science.aao4165. Epub 2017 Nov 16. PMID: 29146868.
- ^ Landskron L, Bak J, Adamopoulos A, Kaplani K, Moraiti Mv, et al. Posttranslational modification of microtubules by the MATCAP detyrosinase. Science. 2022; 376(6595). doi 10.1126/science.abn6020.
Go ahead and feel free to make the changes yourself. Best regards, --Johannes (Talk) (Contribs) (Articles) 18:52, 25 April 2023 (UTC)