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This article was the subject of a Wiki Education Foundation-supported course assignment, between 5 September 2019 and 4 December 2019. Further details are available on the course page. Student editor(s): Reas0ns11. Peer reviewers: KeyLowZip.
This article was the subject of a Wiki Education Foundation-supported course assignment, between 6 September 2018 and 12 December 2018. Further details are available on the course page. Student editor(s): Sakura1997.
Hi,
I'm planning to make the following edits to this page:
Adding a new subtopic called "Structure" which discusses the structure of carboxypeptidase including details about binding site and specificity.
Improving the sentence structure of the subtopic "Activation" plus including more examples of how/when carboxypeptidase is activated, what molecules activate it, and what other precursors are there.
Adding citations to the lead paragraph, "Activation", and "Function".
^Proposed mechanism for carboxypeptidase where water is a nucleophileProposed mechanism for carboxypeptidase via anhydrideBertini, I. (2007). Biological inorganic chemistry (p. 180). Sausalito, Calif.: University Science Books.
@Sakura1997: Please clean-up the artwork. Uniform font (sans-serif). It is incorrect to show the bonding pair of electrons (O-H bond) is the nucleophile that attacks the peptide bond. Easier to draw and more general is to show the lone pair on aquo ligand as the attacking nucleophile. Other less important suggestions: it takes practice, but try to to get curved arrows to mesh perfectly with reaction arrows.--Smokefoot (talk) 18:19, 7 October 2019 (UTC)[reply]
This article was the subject of a Wiki Education Foundation-supported course assignment, between 6 September 2022 and 22 December 2022. Further details are available on the course page. Student editor(s): Vroomvrooms (article contribs).
Hi there, I have made some edits such as talking about the mechanism of carboxypeptidase. This was done by proposing two mechanistic approaches which provides more insight on what happens in the mechanism as previously the only information given about the mechanism was “Carboxypeptidases act by replacing the substrate water with a carbonyl (C=O) group.”. I introduced two mechanistic hypotheses, which allows the reader to understand what happens in the mechanisms. I also added two pictures which show what happens in the mechanisms. Vroomvrooms (talk) 01:44, 6 December 2022 (UTC)[reply]
This article was the subject of a Wiki Education Foundation-supported course assignment, between 5 September 2019 and 4 December 2019. Further details are available on the course page. Student editor(s): Reas0ns11. Peer reviewers: KeyLowZip.
