Talk:Ancestral sequence reconstruction

	This article is within the scope of WikiProject Molecular Biology, a collaborative effort to improve the coverage of Molecular Biology on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.Molecular BiologyWikipedia:WikiProject Molecular BiologyTemplate:WikiProject Molecular BiologyMolecular Biology articles
???	This article has not yet received a rating on the importance scale.
	This article is supported by the Molecular and Cell Biology task force (assessed as Low-importance).

Evolutionary biology Low‑importance

	Evolutionary biology portal This article is part of WikiProject Evolutionary biology, an attempt at building a useful set of articles on evolutionary biology and its associated subfields such as population genetics, quantitative genetics, molecular evolution, phylogenetics, and evolutionary developmental biology. It is distinct from the WikiProject Tree of Life in that it attempts to cover patterns, process and theory rather than systematics and taxonomy. If you would like to participate, there are some suggestions on this page (see also Wikipedia:Contributing FAQ for more information) or visit WikiProject Evolutionary biologyEvolutionary biologyWikipedia:WikiProject Evolutionary biologyTemplate:WikiProject Evolutionary biologyEvolutionary biology articles
Low	This article has been rated as Low-importance on the project's importance scale.

Merge from Paleoenzymology

The Paleoenzymology article covers similar ground as the #Resurrected proteins section of this, it's one of multiple applications of ASR (along with protein engineering). I'd suggest merging it in for now until such time as there is sufficient information to warrant a split. T.Shafee(Evo&Evo)^talk 06:56, 23 April 2019 (UTC)[reply]

I tend to agree although I would prefer to keep them separate, simply because my understanding of Paleoenzymology is more structural: you don't need any seqeunces to study "ancient" enzymes. If you have structures you can do that simply based on the structure(s) of the active site(s) (even though I agree that this may be nearly impossible, given that structural analysis is almost always dependent on sequences). But sure -- a bit more substance would be helpful :) Peteruetz (talk) 00:04, 29 June 2019 (UTC)[reply]

Support merge, given that Paleoenzymology is long-standing stub and is a subset of Ancestral sequence reconstruction. It could certainly have its own section, but it is a subset of the broader topic. There is nothing unique about enzymes compared with other proteins; you still need the sequence, and for any protein you can use current structures to infer likely ancient structure. Functional assays can also be carried out for proteins other than enzymes. Klbrain (talk) 05:33, 5 April 2020 (UTC)[reply]

Merger complete. Klbrain (talk) 20:32, 19 June 2020 (UTC)[reply]