PLD4

PLD4
Identifiers
Aliases	PLD4, C14orf175, phospholipase D family member 4
External IDs	OMIM: 618488; MGI: 2144765; HomoloGene: 16350; GeneCards: PLD4; OMA:PLD4 - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	104,937,761 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	112,735,424 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; monocyte; ; C1 segment; ; bone marrow cells; ; testicle; ; spleen; ; substantia nigra; ; appendix; ; right hemisphere of cerebellum; ; hypothalamus;
	Top expressed in
	spleen; ; white matter of cerebellum; ; bone marrow; ; granulocyte; ; zone of skin; ; white adipose tissue; ; thymus; ; lung; ; jejunum; ; ileum;
	More reference expression data
	n/a
Gene ontology
Molecular function	phospholipase D activity; N-acylphosphatidylethanolamine-specific phospholipase D activity; catalytic activity; hydrolase activity; phosphatidylinositol phospholipase C activity;
Cellular component	integral component of membrane; endoplasmic reticulum membrane; membrane; nucleus; endoplasmic reticulum; trans-Golgi network membrane; phagocytic vesicle;
Biological process	lipid catabolic process; inositol phosphate metabolic process; lipid metabolism; hematopoietic progenitor cell differentiation; phagocytosis;
	Sources:Amigo / QuickGO
Orthologs
	122618
	104759
	ENSG00000166428
	ENSMUSG00000052160
	Q96BZ4
	Q8BG07
	NM_001308174; NM_138790
	NM_178911
	NP_001295103; NP_620145
	NP_849242
	Wikidata
View/Edit Human	View/Edit Mouse

Phospholipase D family member 4 is an enzyme that in humans is encoded by the PLD4 gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000166428 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000052160 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Phospholipase D family, member 4".
^ Universal protein resource accession number Q96BZ4 for "PLD4 - Phospholipase D4 - Homo sapiens" at UniProt.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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v t e Enzymes
Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Diffusion-limited enzyme Cofactor Enzyme catalysis
Regulation	Allosteric regulation Cooperativity Enzyme inhibitor Enzyme activator
Classification	EC number Enzyme superfamily Enzyme family List of enzymes
Kinetics	Enzyme kinetics Eadie–Hofstee diagram Hanes–Woolf plot Lineweaver–Burk plot Michaelis–Menten kinetics
Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list) EC7 Translocases (list)