PAQR8

PAQR8
Identifiers
Aliases	PAQR8, C6orf33, LMPB1, MPRB, progestin and adipoQ receptor family member 8
External IDs	OMIM: 607780; MGI: 1921479; HomoloGene: 32702; GeneCards: PAQR8; OMA:PAQR8 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	52,407,777 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	21,009,874 bp
RNA expression pattern
	Top expressed in
	inferior ganglion of vagus nerve; ; globus pallidus; ; internal globus pallidus; ; subthalamic nucleus; ; external globus pallidus; ; medulla oblongata; ; pars reticulata; ; spinal cord; ; C1 segment; ; mucosa of ileum;
	Top expressed in
	deep cerebellar nuclei; ; lateral geniculate nucleus; ; cerebellar vermis; ; suprachiasmatic nucleus; ; substantia nigra; ; lobe of cerebellum; ; pontine nuclei; ; mammillary body; ; medial geniculate nucleus; ; medial vestibular nucleus;
	More reference expression data
	n/a
Gene ontology
Molecular function	steroid hormone receptor activity; steroid binding; lipid binding; signaling receptor activity;
Cellular component	integral component of membrane; membrane; Golgi apparatus; plasma membrane;
Biological process	multicellular organism development; response to steroid hormone; cell differentiation; oogenesis; steroid hormone mediated signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	85315
	74229
	ENSG00000170915
	ENSMUSG00000025931
	Q8TEZ7
	Q80ZE5
	NM_133367
	NM_028829; NM_001355122
	NP_588608
	NP_083105; NP_001342051
	Wikidata
View/Edit Human	View/Edit Mouse

Membrane progesterone receptor beta (mPRβ), or progestin and adipoQ receptor 8 (PAQR8), is a protein that in humans is encoded by the PAQR8 gene.^[5]^[6]^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000170915 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000025931 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Suzuki T, Ganesh S, Agarwala KL, Morita R, Sugimoto Y, Inazawa J, Delgado-Escueta AV, Yamakawa K (Nov 2001). "A novel gene in the chromosomal region for juvenile myoclonic epilepsy on 6p12 encodes a brain-specific lysosomal membrane protein". Biochemical and Biophysical Research Communications. 288 (3): 626–36. doi:10.1006/bbrc.2001.5825. PMID 11676489.
^ Zhu Y, Rice CD, Pang Y, Pace M, Thomas P (Mar 2003). "Cloning, expression, and characterization of a membrane progestin receptor and evidence it is an intermediary in meiotic maturation of fish oocytes". Proceedings of the National Academy of Sciences of the United States of America. 100 (5): 2231–6. doi:10.1073/pnas.0336132100. PMC 151323. PMID 12574519.
^ "Entrez Gene: PAQR8 progestin and adipoQ receptor family member VIII".

Wistow G, Bernstein SL, Ray S, Wyatt MK, Behal A, Touchman JW, Bouffard G, Smith D, Peterson K (Jun 2002). "Expressed sequence tag analysis of adult human iris for the NEIBank Project: steroid-response factors and similarities with retinal pigment epithelium". Molecular Vision. 8: 185–95. PMID 12107412.
Zhu Y, Bond J, Thomas P (Mar 2003). "Identification, classification, and partial characterization of genes in humans and other vertebrates homologous to a fish membrane progestin receptor". Proceedings of the National Academy of Sciences of the United States of America. 100 (5): 2237–42. Bibcode:2003PNAS..100.2237Z. doi:10.1073/pnas.0436133100. PMC 151324. PMID 12601167.
Hammes SR (Mar 2003). "The further redefining of steroid-mediated signaling". Proceedings of the National Academy of Sciences of the United States of America. 100 (5): 2168–70. Bibcode:2003PNAS..100.2168H. doi:10.1073/pnas.0530224100. PMC 151311. PMID 12606724.
Brandenberger R, Wei H, Zhang S, Lei S, Murage J, Fisk GJ, Li Y, Xu C, Fang R, Guegler K, Rao MS, Mandalam R, Lebkowski J, Stanton LW (Jun 2004). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nature Biotechnology. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197. S2CID 27764390.
Tang YT, Hu T, Arterburn M, Boyle B, Bright JM, Emtage PC, Funk WD (Sep 2005). "PAQR proteins: a novel membrane receptor family defined by an ancient 7-transmembrane pass motif". Journal of Molecular Evolution. 61 (3): 372–80. Bibcode:2005JMolE..61..372T. doi:10.1007/s00239-004-0375-2. PMID 16044242. S2CID 31473802.

This article on a gene on human chromosome 6 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000170915 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000025931 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11676489-5] Suzuki T, Ganesh S, Agarwala KL, Morita R, Sugimoto Y, Inazawa J, Delgado-Escueta AV, Yamakawa K (Nov 2001). "A novel gene in the chromosomal region for juvenile myoclonic epilepsy on 6p12 encodes a brain-specific lysosomal membrane protein". Biochemical and Biophysical Research Communications. 288 (3): 626–36. doi:10.1006/bbrc.2001.5825. PMID 11676489.

[pmid12574519-6] Zhu Y, Rice CD, Pang Y, Pace M, Thomas P (Mar 2003). "Cloning, expression, and characterization of a membrane progestin receptor and evidence it is an intermediary in meiotic maturation of fish oocytes". Proceedings of the National Academy of Sciences of the United States of America. 100 (5): 2231–6. doi:10.1073/pnas.0336132100. PMC 151323. PMID 12574519.

[entrez-7] "Entrez Gene: PAQR8 progestin and adipoQ receptor family member VIII".

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PAQR8

See also

References

Further reading