OR2AP1

OR2AP1
Identifiers
Aliases	OR2AP1, OR2AP1P, olfactory receptor family 2 subfamily AP member 1
External IDs	MGI: 3030601; HomoloGene: 105186; GeneCards: OR2AP1; OMA:OR2AP1 - orthologs
Gene location (Human) Chr. Chromosome 12 (human) Band 12q13.2 Start 55,572,468 bp End 55,575,612 bp
Gene location (Mouse) Chr. Chromosome 10 (mouse) Band 10|10 D3 Start 128,910,694 bp End 128,918,779 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle Top expressed in ileum colon More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell detection of chemical stimulus involved in sensory perception of smell signal transduction response to stimulus G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 121129 258315 Ensembl ENSG00000179615 ENSMUSG00000059762 UniProt Q8NGE2 Q8VG33 RefSeq (mRNA) NM_001258285 NM_146318 RefSeq (protein) NP_001245214 NP_666430 Location (UCSC) Chr 12: 55.57 – 55.58 Mb Chr 10: 128.91 – 128.92 Mb PubMed search
Wikidata
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Olfactory receptor 2AP1 is a protein that in humans is encoded by the OR2AP1 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–2589. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR2AP1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.