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NETO1

From Wikipedia, the free encyclopedia
NETO1
Identifiers
AliasesNETO1, BCTL1, BTCL1, neuropilin and tolloid like 1
External IDsOMIM: 607973; MGI: 2180216; HomoloGene: 16367; GeneCards: NETO1; OMA:NETO1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_144946
NM_001360910

RefSeq (protein)

NP_659195
NP_001347839

Location (UCSC)Chr 18: 72.74 – 72.87 MbChr 18: 86.39 – 86.51 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Neuropilin (NRP) and tolloid (TLL)-like 1 is a protein that in humans is encoded by the NETO1 gene.[5]

Function

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This gene encodes a predicted transmembrane protein containing two extracellular CUB domains followed by a low-density lipoprotein class A (LDLa) domain. A similar gene in mice encodes a protein that plays a critical role in spatial learning and memory by regulating the function of synaptic N-methyl-D-aspartic acid receptor complexes in the hippocampus. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011].

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000166342Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000050321Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Neuropilin (NRP) and tolloid (TLL)-like 1".

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.