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Monoterpene epsilon-lactone hydrolase

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Monoterpene ε-lactone hydrolase
Identifiers
EC no.3.1.1.83
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The enzyme monoterpene ε-lactone hydrolase (EC 3.1.1.83, MLH; systematic name isoprop(en)ylmethyloxepan-2-one lactonohydrolase[1] catalyses the reaction

(1) isoprop(en)ylmethyloxepan-2-one + H2O 6-hydroxyisoprop(en)ylmethylhexanoate (general reaction)
(2) 4-isopropenyl-7-methyloxepan-2-one + H2O 6-hydroxy-3-isopropenylheptanoate
(3) 7-isopropyl-4-methyloxepan-2-one + H2O 6-hydroxy-3,7-dimethyloctanoate

The enzyme catalyses the ring opening of ε-lactones in Gram-positive bacterium Rhodococcus erythropolis DCL14.

References

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  1. ^ van der Vlugt-Bergmans CJ, van der Werf MJ (February 2001). "Genetic and biochemical characterization of a novel monoterpene ε-lactone hydrolase from Rhodococcus erythropolis DCL14". Applied and Environmental Microbiology. 67 (2): 733–41. doi:10.1128/aem.67.2.733-741.2001. PMC 92642. PMID 11157238.
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