Mannosylfructose-phosphate synthase
Appearance
Mannosylfructose-phosphate synthase | |||||||||
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Identifiers | |||||||||
EC no. | 2.4.1.246 | ||||||||
CAS no. | 92480-04-1 (not distinguished from EC 2.4.1.167) | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Mannosylfructose-phosphate synthase (EC 2.4.1.246, mannosylfructose-6-phosphate synthase, MFPS) is an enzyme with systematic name GDP-mannose:D-fructose-6-phosphate 2-alpha-D-mannosyltransferase.[1] This enzyme catalyses the following chemical reaction
- GDP-mannose + D-fructose 6-phosphate GDP + beta-D-fructofuranosyl-alpha-D-mannopyranoside 6F-phosphate
This enzyme, from the soil proteobacterium and plant pathogen Agrobacterium tumefaciens strain C58, requires Mg2+ or Mn2+ for activity.
References
[edit]- ^ Torres LL, Salerno GL (September 2007). "A metabolic pathway leading to mannosylfructose biosynthesis in Agrobacterium tumefaciens uncovers a family of mannosyltransferases". Proceedings of the National Academy of Sciences of the United States of America. 104 (36): 14318–23. doi:10.1073/pnas.0706709104. PMC 1964871. PMID 17728402.
External links
[edit]- Mannosylfructose-phosphate+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)