UDP-glucuronosyltransferase 2B10 is an enzyme that in humans is encoded by the UGT2B10gene.[5][6] It is responsible for glucuronidation of nicotine and cotinine.[7][8]
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Jin CJ, Miners JO, Lillywhite KJ, Mackenzie PI (July 1993). "cDNA cloning and expression of two new members of the human liver UDP-glucuronosyltransferase 2B subfamily". Biochemical and Biophysical Research Communications. 194 (1): 496–503. doi:10.1006/bbrc.1993.1847. PMID8333863.
Chen G, Dellinger RW, Gallagher CJ, Sun D, Lazarus P (March 2008). "Identification of a prevalent functional missense polymorphism in the UGT2B10 gene and its association with UGT2B10 inactivation against tobacco-specific nitrosamines". Pharmacogenetics and Genomics. 18 (3): 181–91. doi:10.1097/FPC.0b013e3282f4dbdd. PMID18300939. S2CID19295110.
Chen G, Blevins-Primeau AS, Dellinger RW, Muscat JE, Lazarus P (October 2007). "Glucuronidation of nicotine and cotinine by UGT2B10: loss of function by the UGT2B10 Codon 67 (Asp>Tyr) polymorphism". Cancer Research. 67 (19): 9024–9. doi:10.1158/0008-5472.CAN-07-2245. PMID17909004.
Kaivosaari S, Toivonen P, Hesse LM, Koskinen M, Court MH, Finel M (September 2007). "Nicotine glucuronidation and the human UDP-glucuronosyltransferase UGT2B10". Molecular Pharmacology. 72 (3): 761–8. doi:10.1124/mol.107.037093. PMID17576790. S2CID6062166.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (October 1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID9373149.
Maruyama K, Sugano S (January 1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID8125298.