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Histidinol-phosphatase

From Wikipedia, the free encyclopedia
histidinol-phosphatase
Histidinol-phosphatase tetramer, Thermus thermophilus
Identifiers
EC no.3.1.3.15
CAS no.9025-79-0
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

The enzyme histidinol-phosphatase (EC 3.1.3.15) catalyzes the reaction

L-histidinol phosphate + H2O L-histidinol + phosphate

This enzyme participates in histidine metabolism.

Nomenclature

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This enzyme belongs to the family of hydrolases, to be specific, those acting on phosphoric monoester bonds. The systematic name is L-histidinol-phosphate phosphohydrolase. Other names in common use include histidinol phosphate phosphatase, L-histidinol phosphate phosphatase, histidinolphosphate phosphatase, HPpase, and histidinolphosphatase.

E. coli

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In E. coli the enzyme encoded by the gene hisB is a fused imidazoleglycerol-phosphate dehydratase and histidinol-phosphatase.[1]

References

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  1. ^ Brilli M, Fani R (February 2004). "Molecular evolution of hisB genes". Journal of Molecular Evolution. 58 (2): 225–237. Bibcode:2004JMolE..58..225B. doi:10.1007/s00239-003-2547-x. PMID 15042344. S2CID 1684458.

Further reading

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